Clinical Trial Update: An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (2 mg/mL IV Solution) on the Pharmacokinetics of Digoxin; Sulfasalazine; and the Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan in Healthy Subjects [Phase 1]

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Summary

This Phase 1 open-label study assessed how a single IV dose of rolapitant affects the pharmacokinetics of digoxin, sulfasalazine, and the Cooperstown Cocktail (…

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Diseases / indications

• Chemotherapy-induced Nausea and Vomiting

Drugs mentioned

• Caffeine (caffeine)
• DIGOXIN (Digoxin)
• Dextromethorphan (dextromethorphan)
• Midazolam (Midazolam)
• Omeprazole (Omeprazole)
• Rolapitant (rolapitant)
• Sulfasalazine (Sulfasalazine)
• Warfarin (warfarin)

Snippet

Sponsor: Tesaro, Inc. | Conditions: Chemotherapy-induced Nausea and Vomiting | Phase 1 | Status: COMPLETED