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CLINICAL_TRIALS research · 2026-04-16

Clinical Trial Update: Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression [Phase 2]

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Summary

Phase 2 clinical trial update investigating the antidepressant effects of 2R,6R-hydroxynorketamine (HNK) as a glutamate-release enhancer for treatment-resistant…

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Diseases / indications

Drugs mentioned

  • (2R,6R)-Hydroxynorketamine (Hydroxynorketamine)

Snippet

Sponsor: National Institute of Mental Health (NIMH) | Conditions: Suicide, Depressive Disorder, Treatment-Resistant | Phase 2 | Status: RECRUITING