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CLINICAL_TRIALS research · 2026-04-20

Clinical Trial Update: Clinical Trial to Evaluate the Safety and Immunogenicity of Ferritin Nanoparticles Expressing Native-like HIV-1 Envelope Trimers Followed by Boost With mRNA Lipid Nanoparticles Encoding a Native-like HIV-1 Envelope Trimer in Adults Without HIV [Phase 1]

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Summary

Phase 1 trial to assess the safety and immunogenicity of ferritin nanoparticle HIV envelope trimers followed by an mRNA lipid nanoparticle boost in adults witho…

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Diseases / indications

Drugs mentioned

  • Ferritin nanoparticle vaccine expressing native-like HIV-1 envelope trimers (ferritin nanoparticle HIV envelope trimer vaccine)
  • mRNA lipid nanoparticle encoding native-like HIV-1 envelope trimer boost (mRNA-LNP HIV envelope trimer booster)

Snippet

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Conditions: Hiv | Phase 1 | Status: ACTIVE_NOT_RECRUITING