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CLINICAL_TRIALS research · 2026-04-21

Clinical Trial Update: A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer [Phase 1, Phase 2]

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Summary

Genentech is evaluating GDC-4198 alone and in combination with giredestrant versus abemaciclib plus giredestrant in locally advanced or metastatic estrogen rece…

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Diseases / indications

Drugs mentioned

  • GDC-4198 (GDC-4198)
  • Giredestrant (giredestrant)
  • VERZENIO (ABEMACICLIB)

Snippet

Sponsor: Genentech, Inc. | Conditions: Breast Cancer | Phase 1, Phase 2 | Status: RECRUITING