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CLINICAL_TRIALS research · 2026-04-22

Clinical Trial Update: Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial [Phase 2]

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Summary

Phase 2 study evaluating the combination of selumetinib with olaparib, or selumetinib alone, for RAS pathway-mutant recurrent or persistent ovarian and endometr…

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Diseases / indications

Drugs mentioned

  • Koselugo (selumetinib)
  • Lynparza (olaparib)

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: Recurrent Endometrial Carcinoma, Recurrent Fallopian Tube Carcinoma | Phase 2 | Status: RECRUITING