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CLINICAL_TRIALS research · 2026-04-24

Clinical Trial Update: Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]

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Summary

This clinical trial update describes the AZA-AEGEAN regimen—neoadjuvant inhaled azacitidine with platinum-based chemotherapy and durvalumab—for operable early-s…

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Diseases / indications

Drugs mentioned

  • Azacitidine (inhaled) (azacitidine)
  • Durvalumab (durvalumab)
  • Platinum-based chemotherapy regimen

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: Non-small Cell Lung Cancer (NSCLC), Carcinoma, Non-Small Cell Lung | Phase 1, Phase 2 | Status: RECRUITING