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CLINICAL_TRIALS ClinicalTrials.gov record update

A Phase 1 Open-label Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PAS-004, a MEK (1/2) Inhibitor, in Patients With MAPK Pathway-driven Advanced Solid Tumors With a Documented RAS, NF1, or RAF Mutation or Patients Who Have Failed BRAF/MEK Inhibition

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Record identity and dates

Source
ClinicalTrials.gov
Source record ID
NCT06299839
Title field or adapter rule
protocolSection.identificationModule.officialTitle
Ingested At
2026-04-25T22:28:54.055779+00:00
Published At
2025-12-03T00:00:00+00:00
Record Updated At
2025-12-03
Timestamp Basis
source retrieval time was not retained by the feed adapter
Date limitation
source retrieval time was not retained by the feed adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions
["RAS Mutation", "NF1 Mutation", "RAF Mutation", "Advanced Solid Tumors"]
protocolSection.statusModule.lastUpdatePostDateStruct.date
"2025-12-03"
protocolSection.identificationModule.nctId
"NCT06299839"
protocolSection.identificationModule.officialTitle
"A Phase 1 Open-label Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PAS-004, a MEK (1/2) Inhibitor, in Patients With MAPK Pathway-driven Advanced Solid Tumors With a Documented RAS, NF1, or RAF Mutation or Patients Who Have Failed BRAF/MEK Inhibition"
protocolSection.statusModule.overallStatus
"RECRUITING"
protocolSection.designModule.phases
["PHASE1"]
protocolSection.statusModule.resultsFirstPostDateStruct.date
""

Study condition terms

  • RAS Mutation (protocolSection.conditionsModule.conditions)
  • NF1 Mutation (protocolSection.conditionsModule.conditions)
  • RAF Mutation (protocolSection.conditionsModule.conditions)
  • Advanced Solid Tumors (protocolSection.conditionsModule.conditions)

Intervention details are not present in the imported fields for this record. No drug-condition relationship is inferred from co-listing.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.