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CLINICAL_TRIALS research · 2025-12-30

Clinical Trial Update: NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer [Phase 3]

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Summary

A Phase 3 clinical trial compares a liposomal irinotecan‑based regimen plus targeted therapy to FOLFOX plus targeted therapy as first-line treatment for metasta…

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Diseases / indications

Drugs mentioned

  • 5-Fluorouracil (5-FU)
  • Leucovorin (folinic acid)
  • Liposome-encapsulated irinotecan (liposomal irinotecan) (irinotecan liposomal formulation)
  • OXALIPLATIN (Oxaliplatin)
  • Targeted therapy

Snippet

Sponsor: Shanghai Zhongshan Hospital | Conditions: Metastatic Colorectal Cancer (CRC) | Phase 3 | Status: RECRUITING