Clinical Trial Update: Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies [Phase 2]

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Summary

Phase 2 trial evaluating sirolimus for safety and efficacy in complicated vascular anomalies has completed. Results were posted on 2026-01-06.

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Diseases / indications

• Capillary-lymphatic-arteriovenous Malformation
• Capillary-venous Malformation
• Kaposiform Hemangioendothelioma
• Microcystic Lymphatic Malformation
• Mucocutaneous Lymphangiomatosis with Thrombocytopenia
• Pten Hamartoma Tumor Syndrome
• Tufted Angioma
• Venous Lymphatic Malformation

Drugs mentioned

• Sirolimus (Sirolimus)

Snippet

Sponsor: Denise Martin Adams | Conditions: Kaposiform Hemangioendotheliomas, Tufted Angioma | Phase 2 | Status: COMPLETED | Results posted: 2026-01-06