Clinical Trial Update: Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel [EARLY_Phase 1]

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Summary

An early Phase 1 trial is evaluating intrathecal dexamethasone and simvastatin to prevent neurotoxicity after axicabtagene ciloleucel therapy in lymphoma; the s…

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Diseases / indications

• Lymphoma

Drugs mentioned

• Axi-cel (axicabtagene ciloleucel)
• DEXAMETHASONE (Dexamethasone)
• SIMVASTATIN (SIMVASTATIN)

Snippet

Sponsor: Masonic Cancer Center, University of Minnesota | Conditions: Lymphoma | EARLY_Phase 1 | Status: ACTIVE_NOT_RECRUITING