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CLINICAL_TRIALS research · 2026-01-12

Clinical Trial Update: Phase 1/2 Study of Avutometinib (VS-6766) + Sotorasib With or Without Defactinib in KRAS G12C NSCLC Patients [Phase 1, Phase 2]

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Summary

Phase 1/2 clinical trial evaluating Avutometinib (VS-6766) with Sotorasib, with or without Defactinib, in KRAS G12C NSCLC; currently active but not recruiting.

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Diseases / indications

Drugs mentioned

  • Avutometinib (avutometinib)
  • Defactinib (defactinib)
  • sotorasib (sotorasib)

Snippet

Sponsor: Verastem, Inc. | Conditions: Non Small Cell Lung Cancer, KRAS Activating Mutation | Phase 1, Phase 2 | Status: ACTIVE_NOT_RECRUITING