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CLINICAL_TRIALS research · 2026-01-13

Clinical Trial Update: Gossypol Acetate + FOLFIRI + Bev in mCRC With TP53-Mutant and LRPPRC Positive [Phase 2]

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Summary

A Phase 2 trial is evaluating gossypol acetate added to FOLFIRI and bevacizumab in metastatic colorectal cancer patients who are TP53-mutant and LRPPRC-positive…

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Diseases / indications

Drugs mentioned

  • 5-Fluorouracil (5-FU)
  • Bevacizumab (bevacizumab)
  • Gossypol acetate (gossypol acetate)
  • Irinotecan (Irinotecan)
  • Leucovorin (folinic acid)

Snippet

Sponsor: Guiying Wang | Conditions: Patients With Metastatic Colorectal Cancer Who Were TP53-mutant and LRPPRC-positive and Had Previously Failed Prior First-line Treatment | Phase 2 | Status: NOT_YET_RECRUITING