Clinical Trial Update: A Phase Ia/Ib Open-label, Multiple Dose, Study to Determine the Recommended Dose, Evaluate PKs, PDs, Safety, and Activity of Venetoclax in Combination With Oral Decitabine/Cedazuridine (ASTX727) in Pediatric Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) [Phase 1]

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Summary

This Phase 1 open-label pediatric study aims to determine the recommended dose and evaluate pharmacokinetics, pharmacodynamics, safety, and activity of venetocl…

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Diseases / indications

• Acute Myeloid Leukemia

Drugs mentioned

• ASTX727 (cedazuridine/decitabine)
• Venetoclax (venetoclax)

Snippet

Sponsor: M.D. Anderson Cancer Center | Conditions: Acute Myeloid Leukemia | Phase 1 | Status: RECRUITING