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CLINICAL_TRIALS research · 2026-03-09

Clinical Trial Update: A Multicenter Two-Cohort Study of Methotrexate, Rituximab, Sintilimab and Pirtobrutinib for Treatment-Naive PCNSL vs. Real-World Investigator-Selected Treatment (Observational Cohort) [Phase 2]

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Summary

This is a Phase 2 multicenter observational study enrolling treatment-naive primary central nervous system lymphoma patients to compare a regimen of methotrexat…

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Diseases / indications

Drugs mentioned

  • METHOTREXATE (METHOTREXATE)
  • Pirtobrutinib (pirtobrutinib)
  • Rituxan (rituximab)
  • Sintilimab (sintilimab)

Snippet

Sponsor: Tongji Hospital | Conditions: PCNSL, Primary Central Nervous System Lymphoma | Phase 2 | Status: RECRUITING