Clinical Trial Update: Neoadjuvant FOLFOXIRI and Chemoradiotherapy Versus Neoadjuvant CAPOX/FOLFOX and Chemoradiotherapy Followed by Surgery or a Watch-and-Wait Approach in High Risk Locally Advanced Rectal Cancer [Phase 3]

View source ↗

Summary

Phase 3 trial comparing neoadjuvant FOLFOXIRI-based chemoradiotherapy with CAPOX/FOLFOX-based chemoradiotherapy, followed by surgery or a watch-and-wait approac…

Upgrade for the full analysis, importance score, and drug timeline.

Diseases / indications

• Rectal Cancer

Drugs mentioned

• CAPOX (XELOX) (capecitabine + oxaliplatin)
• Capecitabine (capecitabine)
• FLUOROURACIL (Fluorouracil)
• FOLFOX
• FOLFOXIRI (folinic acid (leucovorin), fluorouracil (5-FU), oxaliplatin, irinotecan)
• Folinic acid (folinic acid)
• OXALIPLATIN (Oxaliplatin)

Snippet

Sponsor: J. W. A. Burger | Conditions: Locally Advanced Rectal Carcinoma | Phase 3 | Status: NOT_YET_RECRUITING