Clinical Trial Update: A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion [EARLY_Phase 1]

View source ↗

Summary

A pilot Phase 1 trial evaluating larotrectinib for newly diagnosed high-grade glioma with NTRK gene fusions, including diffuse intrinsic pontine glioma.

Upgrade for the full analysis, importance score, and drug timeline.

Diseases / indications

• Diffuse Intrinsic Pontine Glioma
• High-grade Glioma

Drugs mentioned

• Rozlytrek (entrectinib)

Snippet

Sponsor: Nationwide Children's Hospital | Conditions: High Grade Glioma, Diffuse Intrinsic Pontine Glioma | EARLY_Phase 1 | Status: RECRUITING