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CLINICAL_TRIALS research · 2026-03-30

Clinical Trial Update: Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma [Phase 1]

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Summary

Phase 1 study evaluating the safety and feasibility of combining ibrutinib with immunochemotherapy (temozolomide, etoposide, doxorubicin liposomal, dexamethason…

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Diseases / indications

Drugs mentioned

  • DEXAMETHASONE (Dexamethasone)
  • Doxil (liposomal doxorubicin)
  • IMBRUVICA (IBRUTINIB)
  • Rituxan (rituximab)
  • Temodar (Temozolomide)
  • Toposar (Etoposide)

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: Primary Central Nervous System Lymphoma | Phase 1 | Status: ACTIVE_NOT_RECRUITING