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CLINICAL_TRIALS research · 2026-03-31

Clinical Trial Update: A Randomized, Open-label, Multi-center, Phase III Study of Orelabrutinib in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) vs. R-CHOP Alone in Patients With Treatment-naїve Mantle Cell Lymphoma [Phase 3]

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Summary

A Phase III randomized trial evaluating orelabrutinib plus R-CHOP versus R-CHOP alone in treatment-naïve mantle cell lymphoma has completed.

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Diseases / indications

Drugs mentioned

  • CYCLOPHOSPHAMIDE (Cyclophosphamide)
  • Doxorubicin (doxorubicin)
  • Orelabrutinib (orelabrutinib)
  • PREDNISONE (Prednisone)
  • Rituximab (rituximab)
  • Vincristine (vincristine)

Snippet

Sponsor: Beijing InnoCare Pharma Tech Co., Ltd. | Conditions: Treatment-naїve Mantle Cell Lymphoma | Phase 3 | Status: COMPLETED