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CLINICAL_TRIALS research · 2026-04-08

Clinical Trial Update: Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia [Phase 2]

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Summary

Phase 2 clinical trial evaluating DA-EPOCH chemotherapy with or without Rituximab plus recombinant Erwinia asparaginase (JZP458) for newly diagnosed Philadelphi…

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Diseases / indications

Drugs mentioned

  • CYCLOPHOSPHAMIDE (Cyclophosphamide)
  • Doxorubicin (doxorubicin)
  • Etoposide (Etoposide)
  • PREDNISONE (Prednisone)
  • Recombinant Erwinia asparaginase (JZP458) (asparaginase (Erwinia) JZP458)
  • Rituximab (rituximab)
  • Vincristine (vincristine)

Snippet

Sponsor: University of Washington | Conditions: B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, T Acute Lymphoblastic Leukemia | Phase 2 | Status: RECRUITING