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CLINICAL_TRIALS research · 2026-04-13

Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Paclitaxel) and Immunotherapy (Pembrolizumab) for Metastatic Triple-Negative Breast Cancer [Phase 1]

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Summary

A Phase 1 trial is evaluating the addition of ASTX727 (cedazuridine/decitabine) to paclitaxel and pembrolizumab for metastatic or unresectable triple-negative b…

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Diseases / indications

Drugs mentioned

  • ASTX727 (cedazuridine/decitabine)
  • PACLITAXEL (PACLITAXEL)
  • Pembrolizumab (pembrolizumab)

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Phase 1 | Status: RECRUITING