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CLINICAL_TRIALS research · 2026-04-13

Clinical Trial Update: Trial to Evaluate the Safety and Immunogenicity of Priming Regimens of 426c.Mod.Core-C4b and Optional Boost Regimen With HIV Trimer BG505 SOSIP.GT1.1 gp140, Both Adjuvanted With 3M-052-AF + Alum in Healthy, Adult Participants Without HIV [Phase 1]

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Summary

Phase 1 clinical trial evaluating safety and immunogenicity of priming regimens for an HIV vaccine using 426c.Mod.Core-C4b and BG505 SOSIP.GT1.1 gp140, with 3M-…

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Diseases / indications

Drugs mentioned

  • 3M-052 AF (TLR7/8 agonist adjuvant)
  • 426c.Mod.Core-C4b
  • Alum (aluminum-based adjuvant)
  • BG505 SOSIP.GT1.1 gp140

Snippet

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Conditions: HIV-1-infection | Phase 1 | Status: ACTIVE_NOT_RECRUITING