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CLINICAL_TRIALS research · 2026-04-13

Clinical Trial Update: Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy) [Phase 2]

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Summary

Clinical trial update outlining plans to study IDH1 inhibitor olutasidenib in combination with ASTX727 and venetoclax for acute myeloid leukemia, add olutasiden…

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Diseases / indications

Drugs mentioned

  • ASTX727 (cedazuridine/decitabine)
  • Olutasidenib (olutasidenib)
  • Venetoclax (venetoclax)

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome | Phase 2 | Status: NOT_YET_RECRUITING