Phase I/II Study of CDK4/6 Inhibition With Abemaciclib to Upregulate PSMA Expression Prior to 177Lu-PSMA-617 Treatment in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC) Previously Treated With Novel Hormonal Agents and Chemotherapy

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT05113537

Title field or adapter rule

protocolSection.identificationModule.officialTitle

Ingested At

2026-04-25T22:27:56.922197+00:00

Published At

2026-04-13T00:00:00+00:00

Record Updated At

2026-04-13

Timestamp Basis

source retrieval time was not retained by the feed adapter

Date limitation

source retrieval time was not retained by the feed adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Castration-Resistant Prostate Carcinoma", "Metastatic Prostate Adenocarcinoma", "Stage IV Prostate Cancer AJCC v8", "Stage IVA Prostate Cancer AJCC v8", "Stage IVB Prostate Cancer AJCC v8", "Metastatic Castration-resistant Prostate Carcinoma", "Metastatic Castration-resistant Prostate Cancer"]

protocolSection.statusModule.lastUpdatePostDateStruct.date

"2026-04-13"

protocolSection.identificationModule.nctId

"NCT05113537"

protocolSection.identificationModule.officialTitle

"Phase I/II Study of CDK4/6 Inhibition With Abemaciclib to Upregulate PSMA Expression Prior to 177Lu-PSMA-617 Treatment in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC) Previously Treated With Novel Hormonal Agents and Chemotherapy"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["PHASE1", "PHASE2"]

protocolSection.statusModule.resultsFirstPostDateStruct.date

""

Study condition terms

• Castration-Resistant Prostate Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Prostate Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Stage IV Prostate Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IVA Prostate Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IVB Prostate Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Metastatic Castration-resistant Prostate Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Castration-resistant Prostate Cancer (protocolSection.conditionsModule.conditions)

Intervention details are not present in the imported fields for this record. No drug-condition relationship is inferred from co-listing.

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