Clinical Trial Update: Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas [Phase 1]

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Summary

Phase 1 trial evaluating the safety and tolerability of a multi-agent regimen including ibrutinib, rituximab, etoposide, prednisone, vincristine, cyclophosphami…

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Diseases / indications

• Aids-related Lymphoma
• Diffuse Large B-cell Lymphoma

Drugs mentioned

• Adriamycin (doxorubicin)
• Cytoxan (cyclophosphamide)
• Deltasone (prednisone)
• IMBRUVICA (IBRUTINIB)
• Oncovin (vincristine)
• Rituxan (rituximab)
• VePesid (etoposide)

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: AIDS-Related Lymphoma, Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | Phase 1 | Status: ACTIVE_NOT_RECRUITING | Results posted: 2026-04-02