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CLINICAL_TRIALS research · 2025-05-20

Clinical Trial Update: Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal Metastasis [Phase 1, Phase 2]

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Summary

A Phase 1/2 clinical trial is investigating intrathecal administration of a PD-1/CTLA-4 bispecific antibody with pemetrexed for leptomeningeal metastasis; the s…

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Diseases / indications

Drugs mentioned

  • PD-1/CTLA-4 bispecific antibody
  • Pemetrexed (pemetrexed)

Snippet

Sponsor: Guangzhou Medical University | Conditions: Leptomeningeal Metastasis | Phase 1, Phase 2 | Status: RECRUITING