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CLINICAL_TRIALS research · 2025-06-15

Clinical Trial Update: AK112 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI as Second-line Treatment of MSS/pMMR Metastatic Colorectal Cancer [Phase 2]

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Summary

A Phase 2 trial compares AK112 (ivonescimab) plus FOLFIRI to bevacizumab plus FOLFIRI as second-line therapy for MSS/pMMR metastatic colorectal cancer; the stud…

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Diseases / indications

Drugs mentioned

  • 5-Fluorouracil (5-FU)
  • AK112
  • Bevacizumab (bevacizumab)
  • Irinotecan (Irinotecan)
  • Leucovorin (folinic acid)

Snippet

Sponsor: Sun Yat-sen University | Conditions: Colorectal Cancer, Ivonescimab | Phase 2 | Status: NOT_YET_RECRUITING