Clinical Trial Update: Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane [Phase 1]

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Summary

A Phase 1 trial tested whether early administration of dexrazoxane can prevent doxorubicin-induced heart failure; the study is completed and results have been p…

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Diseases / indications

• Doxorubicin-induced Cardiomyopathy
• Heart Failure

Drugs mentioned

• DEXRAZOXANE (DEXRAZOXANE)
• Doxorubicin (doxorubicin)

Snippet

Sponsor: University of Arkansas | Conditions: Degradation of Top2b and Top2a in Human by Dexrazoxane, Time Course and Degradation of Top2b in Human by Dexrazoxane | Phase 1 | Status: COMPLETED | Results posted: 2025-06-12