Wet Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO6867461 Administered in Single- and Multiple-Ascending Doses in Patients With Wet Age-Related Macular Degeneration [Phase 1]
A Phase 1 study of RO6867461 in single- and multiple-ascending dose cohorts for wet age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Pilot Study of Lucentis Combined With Proton Beam Irradiation in Treating Wet Age-related Macular Degeneration [EARLY_Phase 1]
An early-phase pilot study evaluated Lucentis (ranibizumab) in combination with proton beam irradiation for wet age-related macular degenera…
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: A 4 Week Study With BI 144807 in Patients >= 50 Years With Wet Age Related Macular Degeneration [Phase 2]
A 4-week Phase 2 trial of BI 144807 in adults 50 and older with wet age-related macular degeneration completed, with results posted on 2016-…
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CLINICAL_TRIALS trial_result · 2016-05-23Clinical Trial Update: Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting
A completed real-world study evaluating the effectiveness and safety of ranibizumab in patients with wet age-related macular degeneration, d…
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CLINICAL_TRIALS trial_result · 2015-10-30Clinical Trial Update: Treat and Extend Therapy Study Using Intravitreal Aflibercept for Patients Exited From Protocol VGFT-OD 0910 [Phase 4]
Phase 4 clinical trial update describing a treat-and-extend study of intravitreal aflibercept for patients who exited protocol VGFT-OD 0910 …
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CLINICAL_TRIALS trial_result · 2015-09-14Clinical Trial Update: Non-Persistence/Non-Adherence (NP/NA) in Wet Age-related Macular Degeneration (wAMD) Patients in Germany
A Bayer-sponsored clinical trial conducted in Germany examined non-persistence and non-adherence in patients with wet age-related macular de…
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CLINICAL_TRIALS trial_result · 2015-03-13Clinical Trial Update: VEGF Trap-Eye: Investigation of Efficacy and Safety in Chinese Subjects With Wet AMD (Age-Related Macular Degeneration) [Phase 3]
Phase 3 clinical trial update assessing efficacy and safety of VEGF Trap-Eye (aflibercept) in Chinese patients with wet age-related macular …
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: Phase 1 Safety Study With Intravitreal (IVT) REGN2176-3 in Patients Aged 50 Years and Older With Wet AMD [Phase 1]
This update reports the completion of a Phase 1 intravitreal safety study of REGN2176-3 in adults 50 years and older with wet age-related ma…
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CLINICAL_TRIALS trial_result · 2014-12-17Clinical Trial Update: Analysis of Growth Factors in Patients Undergoing Lucentis or Avastin Injections for Diabetic Macular Edema and Exudative Macular Degeneration [NA]
Clinical trial update analyzing growth factors in patients receiving Lucentis or Avastin injections for diabetic macular edema and wet age-r…
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: INTREPID - IRay Plus Anti-VEGF Treatment For Patients With Wet AMD [Phase 2]
INTREPID is a Phase 2 trial evaluating IRay Plus in combination with anti-VEGF treatment for wet age-related macular degeneration. The study…
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Safety & Efficacy Study Evaluating the Combination of Bevasiranib & Lucentis Therapy in Wet AMD [Phase 3]
Phase 3 trial evaluating Bevasiranib plus Lucentis for wet age-related macular degeneration was terminated, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: Study to Assess the EffectiVeness of exIsting Anti-vascular Endothelial groWth Factor (Anti-VEGF) Treatment Regimens in Patients With Wet Age-related Macular Degeneration
This completed clinical trial evaluated the effectiveness of existing anti-VEGF treatment regimens in patients with wet age-related macular …
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CLINICAL_TRIALS trial_result · 2014-07-22Clinical Trial Update: An Open, Single-center, Safety and Efficacy Study of Conbercept in Patients With Very Low Vision Secondary to Wet Age-related Macular Degeneration (wAMD) [Phase 2]
This open, single-center Phase 2 trial evaluates the safety and efficacy of Conbercept in patients with very low vision due to wet age-relat…
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CLINICAL_TRIALS trial_result · 2014-05-12Clinical Trial Update: Study of MP0112 Intravitreal Injection in Patients With Wet Age Related Macular Degeneration [Phase 1]
Allergan's Phase 1 trial of MP0112 given by intravitreal injection for wet age-related macular degeneration was terminated; results were pos…
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CLINICAL_TRIALS trial_result · 2014-05-07Clinical Trial Update: ESBA1008 Safety, Tolerability and Effects in Wet Age-Related Macular Degeneration (AMD) Patients [Phase 1, Phase 2]
Update on ESBA1008 in wet age-related macular degeneration assessing safety, tolerability, and preliminary effects in Phase 1/2. The trial i…
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CLINICAL_TRIALS trial_result · 2014-01-27Clinical Trial Update: Study to Assess the Effectiveness of Existing Anti vascUlar Endothelial Growth Factor (Anti VEGF) in Patients With Wet Age-related Macular Degeneration (wAMD) (AURA)
This completed clinical trial (AURA) evaluated the effectiveness of existing anti-VEGF therapy for wet age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2013-06-17Clinical Trial Update: Omega-3 Supplementation and Vitreal VEGF Levels in Wet-AMD [NA]
A completed clinical trial evaluated whether omega-3 fatty acid supplementation influences vitreous VEGF levels in wet age-related macular d…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Evaluation of AL-78898A in Exudative Age-Related Macular Degeneration [Phase 2]
Phase 2 clinical trial evaluating AL-78898A for wet age-related macular degeneration has completed, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-04-26Clinical Trial Update: An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration [Phase 2]
An open-label Phase 2 clinical trial evaluating the clinical and economic benefits of the I-Ray radiation therapy system for choroidal neova…
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CLINICAL_TRIALS trial_result · 2012-12-19Clinical Trial Update: A Prospective Study Comparing Ranibizumab Plus Dexamethasone Combination Therapy Versus Ranibizumab Monotherapy for Wet AMD [Phase 1, Phase 2]
A completed Phase 1/2 prospective trial comparing ranibizumab plus dexamethasone versus ranibizumab monotherapy for wet age-related macular …
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CLINICAL_TRIALS trial_result · 2012-05-28Clinical Trial Update: Investigates Improvement in Vision Following Switching From Avastin and Macugen Over to Lucentis
A clinical trial update reports vision improvement when wet age-related macular degeneration patients switch from Avastin and Macugen to Luc…
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CLINICAL_TRIALS trial_result · 2012-04-16Clinical Trial Update: Vascular Endothelial Growth Factor VEGF Trap-Eye:Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration(AMD) [Phase 3]
Phase 3 results update for VEGF Trap-Eye (aflibercept) in wet age-related macular degeneration, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-04-12Clinical Trial Update: Lucentis for Age-related Macular Degeneration Pigment Epithelial Detachments [Phase 2, Phase 3]
A completed Phase 2/Phase 3 clinical trial evaluating Lucentis (ranibizumab) for age-related macular degeneration with pigment epithelial de…
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CLINICAL_TRIALS trial_result · 2012-03-01Clinical Trial Update: Safety and Efficacy of Repeated Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Wet Age-Related Macular Degeneration (AMD) [Phase 2]
This ClinicalTrials.gov update reports results from a Phase 2 study evaluating repeated intravitreal VEGF Trap (aflibercept) injections for …
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CLINICAL_TRIALS trial_result · 2012-01-23Clinical Trial Update: Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD) [Phase 3]
Phase 3 results update on VEGF Trap-Eye (aflibercept) for wet age-related macular degeneration, with trial outcomes posted in 2012.