Wet Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK [Phase 3]
Phase 3 study evaluating Tarcocimab Tedromer and Tabirafusp Tedromer versus Aflibercept in wet age-related macular degeneration; status ACTI…
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CLINICAL_TRIALS trial_result · 2026-04-28Clinical Trial Update: Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMD [Phase 2, Phase 3]
Pivotal Phase 2/3 study of ABBV-RGX-314 (RGX-314) gene therapy for neovascular age-related macular degeneration evaluates subretinal deliver…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: NT-101 Topical Ophthalmic Solution in Patients With Wet AMD [Phase 1, Phase 2]
This is a clinical trial update for NT-101 Topical Ophthalmic Solution in patients with wet age-related macular degeneration, covering Phase…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT]
This entry provides an update on the OPTIC-EXT long-term extension study of ADVM-022 for wet age-related macular degeneration. The trial is …
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: A Study to Compare JL14002 to Lucentis® in Subjects With Wet Age-related Macular Degeneration (wAMD) [Phase 3]
A Phase 3 study comparing JL14002 to Lucentis for wet age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Macular Degeneration [Phase 3]
Phase 3 efficacy evaluation comparing BAT5906 to Lucentis in neovascular age-related macular degeneration has completed, with efficacy data …
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK [Phase 3]
Phase 3 DAYBREAK trial evaluating the efficacy and safety of two investigational agents (Tarcocimab Tedromer and Tabirafusp Tedromer) agains…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) [Phase 2]
The Phase 2 study of EYP-1901 in wet age-related macular degeneration has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Safety and Efficacy of Oral HX9428 Tablets in Subjects With Wet Age-related Macular Degeneration (wAMD) [Phase 1, Phase 2]
This document reports a Phase 1/2 clinical trial evaluating the safety and efficacy of oral HX9428 tablets in patients with wet age-related …
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Clinical Study for the Evaluation of Safety and Tolerability of SCAI-005 Eye Drops [Phase 1]
This is a Phase 1 study evaluating the safety and tolerability of SCAI-005 Eye Drops for Wet Age-Related Macular Degeneration. The trial sta…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: AAVCAGsCD59 for the Treatment of Wet AMD [Phase 1]
Phase 1 clinical trial evaluating AAVCAGsCD59 for wet age-related macular degeneration has been completed.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Compare the Efficacy and Safety of HLX04-O with Ranibizumab in Subjects with WAMD [Phase 3]
Phase 3 trial comparing HLX04-O with Ranibizumab in wet age-related macular degeneration was completed, evaluating efficacy and safety. The …
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD) [Phase 3]
Phase 3 clinical effectiveness study of ONS-5010 for neovascular age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Cool vs Room-temperature Artificial Tears [Phase 4]
Phase 4 clinical trial comparing cool versus room-temperature artificial tears has completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Efficacy and Safety of AL-001 Ophthalmic Injection in Subjects with WAMD [Phase 2]
This update reports on a Phase 2 trial evaluating the efficacy and safety of AL-001 ophthalmic injection in wet age-related macular degenera…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: A Phase 3 Study to Compare the Efficacy and Safety of HLX04-O with Ranibizumab in Subjects with WAMD [Phase 3]
A Phase 3 trial evaluating HLX04-O versus Ranibizumab in wet age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: A Study to Test Different Doses of BI 836880 in Patients With an Eye Disease Called Wet Age-related Macular Degeneration (wAMD) [Phase 1, Phase 2]
The study tested multiple doses of BI 836880 in patients with wet age-related macular degeneration; the Phase 1/2 trial has completed and re…
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CLINICAL_TRIALS trial_result · 2024-09-20Clinical Trial Update: Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease
This clinical trial update reports the completion of a Bayer-sponsored study evaluating proactive treatments for patients with wet age-relat…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration. [Phase 2, Phase 3]
Phase 2/Phase 3 trial comparing KSI-301, a biopolymer-conjugated anti-VEGF antibody, against aflibercept in wet age-related macular degenera…
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy [Phase 2]
This Phase 2 clinical trial update covers long-term follow-up of RGX-314 in neovascular age-related macular degeneration, including a fellow…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) [Phase 3]
Phase 3 head-to-head trial evaluating intravitreal KSI-301 versus intravitreal aflibercept in wet age-related macular degeneration has compl…
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CLINICAL_TRIALS trial_result · 2024-04-16Clinical Trial Update: Clinical Study on the Efficacy and Safety of BAT5906 Injection [Phase 2]
Phase 2 trial update on BAT5906 injection assessing efficacy and safety in wet age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: A Study to Comparing SCD411 and Eylea® in Subjects With Wet Age-related Macular Degeneration (AMD) [Phase 3]
Phase 3 trial comparing SCD411 to Eylea in wet/ neovascular age-related macular degeneration has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: Efficacy and Safety of RC28-E Versus Aflibercept [Phase 3]
Phase 3 trial update comparing RC28-E to aflibercept for wet age-related macular degeneration; efficacy and safety data not yet available in…
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: A Phase II Study of RBM-007 Alone and RBM-007 With Eylea® in Subjects With Wet Age-related Macular Degeneration [Phase 2]
Phase II study assessing RBM-007 alone and with Eylea in wet age-related macular degeneration has completed with results posted.