Wet Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) [Phase 2, Phase 3]
EyeBiotech's MK-8748 (EYE201) is in a Phase 2/3 trial for macular degeneration, including age-related macular degeneration, with recruitment…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003) [Phase 2, Phase 3]
Phase 2/3 trial MK-8748 (EYE201) for age-related macular degeneration is described in this update. The study status is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56 [Phase 3]
Phase 3 clinical trial update for EYP-1901 in wet age-related macular degeneration; primary efficacy to be determined at Week 56 in a 2-year…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: MMP-9 Inhibition for Recalcitrant Wet AMD [Phase 2]
Phase 2 clinical trial investigating inhibitors of MMP-9 for recalcitrant wet age-related macular degeneration; currently recruiting.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56 [Phase 3]
A Phase 3 trial (LUCIA) evaluating EYP-1901 for wet age-related macular degeneration is ongoing, with primary efficacy to be determined at W…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Study of the SCD411 Prefilled Syringe for Treating Adults With Wet Age-Related Macular Degeneration, Retinal Vein Occlusion, Diabetic Macular Edema, or Diabetic Retinopathy [Phase 2]
A Phase 2 study of SCD411 in adults with wet age-related macular degeneration, retinal vein occlusion, diabetic macular edema, or diabetic r…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) [Phase 3]
Phase 3 trial AQUARIUS is evaluating the efficacy and safety of Ixo-vec (Ixoberogene soroparvovec) in neovascular/wet age-related macular de…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Efficacy and Safety of LX102 Gene Therapy in Patients With Neovascular Age-related Macular Degeneration (nAMD) (STELLAR) [Phase 3]
A Phase 3 clinical trial assessing the efficacy and safety of LX102 Gene Therapy for neovascular age-related macular degeneration (nAMD) is …
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: User-centric Study of Patients' Receptiveness Towards the Web-based Automated Vision Impairment Gaze-tracking Analysis Systems
Tan Tock Seng Hospital is conducting a user-centric study to assess patients' receptiveness to a web-based automated gaze-tracking analysis …
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Automated Vision Assessment and Impairment Detection Through Gaze Analysis in Wet AMD Patients
A clinical trial update on automated vision assessment and impairment detection using gaze analysis in patients with age-related macular deg…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Comparison of Rapid Aflibercept and Brolucizumab T&E in wAMD [NA]
This clinical trial compares rapid aflibercept versus brolucizumab with a treat-and-extend approach in wet age-related macular degeneration …
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration [Phase 3]
A Phase 3 study evaluating efficacy and safety of Ixoberogene Soroparvovec (Ixo-vec) for neovascular age-related macular degeneration is cur…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: High Dose (HD) Aflibercept Switch in Neovascular Age-related Macular Degeneration (nAMD): to Load or Maintain (HEIRLOOM) [Phase 3]
Phase 3 trial HEIRLOOM evaluating high-dose aflibercept switching (load vs maintain) for wet/neovascular age-related macular degeneration.
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: A Long-term Follow up Study of EXG102-031 in Participants With wAMD
A long-term follow-up study of EXG102-031 for wet age-related macular degeneration is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Optimizing the Treatment Strategy for Age-related Macular Degeneration [NA]
This clinical trial update discusses optimizing treatment strategies for wet age-related macular degeneration. The trial is currently active…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: To Evaluate the Safety and Preliminary Efficacy of Intravitreal EXG202 Injection in Patients with Wet (neovascular) Age-related Macular Degeneration (wAMD) [EARLY_Phase 1]
This clinical trial update outlines a Phase 1 intravitreal study of EXG202 for wet age-related macular degeneration, focusing on safety and …
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Safety and Tolerability of AL-001 Ophthalmic Injection in Subjects with WAMD [Phase 1, Phase 2]
Phase 1/2 trial update on the safety and tolerability of AL-001 ophthalmic injections in patients with wet age-related macular degeneration;…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Comparing Efficacy of 8-Week and 12-Week Faricimab Initial Follow-Up Treatment Intervals [Phase 4]
This clinical trial update describes an ongoing Phase 4 study comparing 8-week versus 12-week initial follow-up treatment intervals for fari…
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: The Effect of Phacoemulsification on the Macular Changes in Patients with Neovascular Age-related Macular Degeneration
This clinical trial update examines whether phacoemulsification (cataract surgery) impacts macular changes in patients with wet age-related …
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Long-term Follow-up Study of AL-001 Ophthalmic Injection in Subjects with WAMD
A long-term follow-up study of AL-001 ophthalmic injection for wet age-related macular degeneration is currently recruiting.
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CLINICAL_TRIALS research · 2019-02-15Clinical Trial Update: To Describe the Use of Intravitreal Aflibercept and to Describe Follow-up as Well as Treatment Patterns in Patients With Wet Age-related Macular Degeneration (wAMD) or Diabetic Macular Edema (DME) in Routine Clinical Practice in Canada.
A clinical trial update describing real-world use of intravitreal aflibercept and follow-up/treatment patterns for wet age-related macular d…
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CLINICAL_TRIALS research · 2017-08-22Clinical Trial Update: Caregiver Burden of Wet Age-related Macular Degeneration (wAMD) in Japan
Bayer-sponsored clinical trial in Japan evaluating caregiver burden in patients with wet age-related macular degeneration has completed.
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CLINICAL_TRIALS research · 2011-07-27Clinical Trial Update: A Study of the NeoVista Ophthalmic System for the Treatment of Subfoveal CNV Associated With Wet AMD in Patients That Require Persistent Anti-VEGF Therapy [Phase 1, Phase 2]
Update on a Phase 1/2 study evaluating the NeoVista Ophthalmic System for treating subfoveal CNV associated with wet age-related macular deg…
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CLINICAL_TRIALS research · 2011-02-09Clinical Trial Update: Sub-tenon Triamcinolone Acetonide in Age-Related Macular Degeneration as Adjunct to Ranibizumab [Phase 2]
Phase 2 clinical trial evaluating sub-tenon Triamcinolone acetonide as an adjunct to Ranibizumab for wet age-related macular degeneration. C…
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CLINICAL_TRIALS research · 2010-06-09Clinical Trial Update: Posterior Macular Adhesion: A Potential Risk Factor for Non-exudative Age Related Macular Degeneration (AMD) to Develop Exudative AMD
A clinical trial update investigates posterior macular adhesion as a potential risk factor for progression from dry age-related macular dege…