Ventilator-associated Pneumonia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: VITAL - VAP Prevention by BIP (Bactiguard Infection Protection) ETT Evac in Belgian ICUs [Phase 4]
Phase 4 trial update on Bactiguard ETT Evac device for preventing ventilator-associated pneumonia in Belgian ICUs.
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CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: Effect of Angulus on Patient-elevation Compliance [NA]
Clinical trial completed investigating Angulus and its impact on patient-elevation compliance in ventilated patients; results posted in 2021…
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens [Phase 3]
Phase 3 trial evaluating Cefiderocol (S-649266) versus best available therapy for severe infections due to carbapenem-resistant Gram-negativ…
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial [Phase 4]
Phase 4 trial evaluating probiotics to prevent severe pneumonia and endotracheal colonization in ventilated patients; trial completed.
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CLINICAL_TRIALS trial_result · 2020-11-13Clinical Trial Update: Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pathogens [Phase 3]
Phase 3 clinical trial of Cefiderocol for healthcare-associated pneumonia and hospital-acquired pneumonia has completed with results posted …
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CLINICAL_TRIALS trial_result · 2020-07-13Clinical Trial Update: Low Versus High Corticosteroid Use in Ventilator Associated Pneumonia [Phase 2]
Phase 2 trial comparing low versus high corticosteroid use in ventilator-associated pneumonia has completed.
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CLINICAL_TRIALS trial_result · 2020-07-01Clinical Trial Update: Umbilical Cord(UC)-Derived Mesenchymal Stem Cells(MSCs) Treatment for the 2019-novel Coronavirus(nCOV) Pneumonia [Phase 2]
Phase 2 clinical trial exploring umbilical cord-derived mesenchymal stem cells for viral pneumonia due to a novel coronavirus; current statu…
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CLINICAL_TRIALS trial_result · 2020-03-18Clinical Trial Update: Antibiotherapy During Therapeutic Hypothermia to Prevent Infectious Complications [Phase 3]
Phase 3 trial evaluating antibiototherapy during therapeutic hypothermia to prevent infectious complications in patients with ventilator-ass…
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CLINICAL_TRIALS withdrawal · 2019-10-09Clinical Trial Update: Randomized-controlled Trial (RCT) on Combination Antibiotic for Infections Caused by Gram-negative Bacteria [Phase 2, Phase 3]
A randomized-controlled trial evaluating a combination antibiotic for gram-negative infections (bacteremia and healthcare-associated pneumon…
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial [Phase 2]
A Phase 2 feasibility trial evaluating probiotics for prevention of severe pneumonia and endotracheal colonization in mechanically ventilate…
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CLINICAL_TRIALS trial_result · 2019-08-14Clinical Trial Update: Methods of Chlorhexidine Cleansing to Prevent Ventilator-Associated Pneumonia (VAP) [Phase 2]
Phase 2 clinical trial update on chlorhexidine cleansing methods to prevent ventilator-associated pneumonia.
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FDA approval · 2019-07-16FDA Approved: RECARBRIO — Original Application (Merck Sharp & Dohme LLC)
FDA approved RECARBRIO (imipenem/cilastatin/relebactam) under NDA 212819 from Merck Sharp & Dohme LLC, marking the original approval of this…
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FDA approval · 2019-06-03FDA Approved: ZERBAXA — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approved a supplemental application for ZERBAXA (ceftolozane and tazobactam) from Merck, resulting in changes to the product labeling.
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CLINICAL_TRIALS trial_result · 2019-05-31Clinical Trial Update: Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia (MK-7625A-008) [Phase 3]
Phase 3 safety and efficacy study of ceftolozane/tazobactam for ventilated nosocomial pneumonia has completed with posted results.
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FDA approval · 2019-03-14FDA Approved: AVYCAZ — Supplemental Application (Allergan, Inc.)
FDA approved a supplemental application for AVYCAZ (ceftazidime-avibactam) that updates labeling in connection with the supplement.
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CLINICAL_TRIALS trial_result · 2019-03-11Clinical Trial Update: Different Oral Colonization of Gram-negative Bacteria in ICU Patients When Using Chlorhexidine at 0.12% Versus Chlorhexidine at 2.0% [Phase 3]
Phase 3 trial investigating how different chlorhexidine concentrations (0.12% vs 2.0%) affect oral colonization by Gram-negative bacteria in…
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: To Compare Endotracheal Tube (ET) With Subglottic Suction Drainage and Standard ET in the Incidence of VAP [NA]
This clinical trial compared endotracheal tubes with subglottic suction drainage to standard endotracheal tubes to assess the incidence of v…
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CLINICAL_TRIALS withdrawal · 2019-01-11Clinical Trial Update: A Study of Meropenem-Vaborbactam Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia [Phase 3]
Phase 3 trial comparing meropenem-vaborbactam to piperacillin/tazobactam for hospital-acquired and ventilator-associated bacterial pneumonia…
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CLINICAL_TRIALS trial_result · 2018-08-13Clinical Trial Update: Nebulized and Intravenous Colistin in Ventilator Associated-pneumonia [Phase 3]
Phase 3 clinical trial evaluating nebulized and intravenous colistin for ventilator-associated pneumonia has been terminated.
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CLINICAL_TRIALS trial_result · 2018-08-09Clinical Trial Update: The Effect of Colistin Inhalation on Ventilator Associated Pneumonia [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating inhaled colistin for treatment of ventilator-associated pneumonia has completed.
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CLINICAL_TRIALS trial_result · 2018-07-31Clinical Trial Update: Assesment of the Endotracheal Tube Cuff Pressure Values in ICU Pateints Before and After Training Seminar [NA]
A completed clinical study evaluating endotracheal tube cuff pressure in ICU patients before and after a staff training seminar to assess ch…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Early Detection of Ventilator-associated Pneumonia (VAP) [NA]
Update on a completed clinical trial evaluating early detection of ventilator-associated pneumonia.
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: Chlorhexidine vs Lactobacillus Plantarum for Oral Care in Intubated ICU Patients [NA]
A completed clinical trial compared chlorhexidine versus Lactobacillus plantarum for oral care in intubated ICU patients, evaluating effects…
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: Study of Different Etiologic Diagnostic Methods in Ventilator Associated Pneumonia (VAP)
A clinical trial evaluating different etiologic diagnostic methods for ventilator-associated pneumonia was terminated.
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CLINICAL_TRIALS trial_result · 2018-05-02Clinical Trial Update: Study of Cases of Serious Infections Due to Carbapenem-Resistant Enterobacteriaceae
Completed clinical trial investigating cases of serious infections due to carbapenem-resistant Enterobacteriaceae across multiple infection …