Valvular Heart Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-10-18Clinical Trial Update: Normothermiс Cardiopulmonary Bypass Increases Cerebral Oxygenation During Valve Surgery [NA]
A completed clinical trial update indicates that normothermic cardiopulmonary bypass during valve surgery increases cerebral oxygenation.
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FDA approval · 2012-03-27FDA Approved: JANTOVEN — Supplemental Application (Upsher-Smith Laboratories, LLC)
FDA approved a supplemental application for Jantoven (warfarin sodium) submitted by Upsher-Smith Laboratories.
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CLINICAL_TRIALS research · 2012-03-19Clinical Trial Update: Multicenter Study on Fibrotic Valvular Heart Disease in Patients With Parkinson's Disease Treated With Dopamine Agonists
A multicenter clinical trial update investigating fibrotic valvular heart disease in patients with Parkinson's disease treated with dopamine…
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CLINICAL_TRIALS research · 2011-12-06Clinical Trial Update: Observational Study of Heart Valve Disease in Patients With Parkinson's Disease Treated With Pergolide
An observational study update examining the risk of heart valve disease in Parkinson's disease patients treated with pergolide.
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CLINICAL_TRIALS trial_result · 2011-09-01Clinical Trial Update: Effect of Combined Remote Ischemic Preconditioning and Postconditioning on Acute Pulmonary Injury in Patients Undergoing Valvular Heart Surgery [Phase 4]
Phase 4 clinical trial evaluating whether combined remote ischemic preconditioning and postconditioning reduces acute pulmonary injury in pa…
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CLINICAL_TRIALS trial_result · 2011-01-13Clinical Trial Update: Comparison of Goal-directed Algorithms of Hemodynamic Therapy After Combined Valve Repair [NA]
This entry notes the completion of a clinical trial comparing goal-directed hemodynamic therapy algorithms after combined valve repair in va…
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CLINICAL_TRIALS trial_result · 2011-01-04Clinical Trial Update: Choice of Valve Substitute in the Era of Oral Anticoagulation Self-Management
This clinical trial update reports completion of a study comparing valve substitute options for patients with mechanical heart valves on sel…
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CLINICAL_TRIALS trial_result · 2010-12-14Clinical Trial Update: Benefit of Self-monitoring of Anticoagulation Instrument [NA]
A completed clinical trial evaluating the benefit of a self-monitoring instrument for patients on oral anticoagulation undergoing mechanical…
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CLINICAL_TRIALS research · 2010-11-11Clinical Trial Update: Persistent Pulmonary Artery Hypertension After Valve Replacement
Clinical trial update on persistent severe pulmonary hypertension after valve replacement. The current trial status is unknown.
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CLINICAL_TRIALS trial_result · 2010-11-04Clinical Trial Update: MPAACS: Magnesium for the Prevention of Atrial Arrhythmias After Cardiac Surgery [Phase 3]
Phase 3 trial evaluating magnesium to prevent atrial arrhythmias after cardiac surgery was terminated.
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CLINICAL_TRIALS trial_result · 2010-10-07Clinical Trial Update: Effect of Preoperative Recombinant Human Erythropoietin on Transfusion Risk in Valvular Heart Surgery [NA]
Completed trial evaluating whether preoperative recombinant human erythropoietin reduces transfusion risk in valvular heart surgery.
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CLINICAL_TRIALS trial_result · 2009-09-07Clinical Trial Update: Patients Perception of Mechanical Heart Valve Sounds: Psychoacoustics and Quality of Life
This clinical trial update reports on patients' perception of the sounds produced by mechanical heart valves and how these psychoacoustic fa…
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CLINICAL_TRIALS research · 2009-09-03Clinical Trial Update: VKORC1 and CYP2C9 Gene Polymorphisms and Warfarin Management
Update on a pharmacogenomics study examining how VKORC1 and CYP2C9 polymorphisms affect warfarin management across several indications, incl…
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CLINICAL_TRIALS trial_result · 2009-05-21Clinical Trial Update: Preparation of Patients for Cardiac Surgery [Phase 3]
Phase 3 clinical trial update on methods for preparing patients undergoing coronary artery bypass graft surgery or cardiac valve surgery. Th…
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CLINICAL_TRIALS trial_result · 2008-05-12Clinical Trial Update: Heart Valve Prosthesis-Patient Mismatch
Clinical trial evaluating a heart valve prosthesis and the occurrence of prosthesis-patient mismatch has completed.
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CLINICAL_TRIALS research · 2008-04-15Clinical Trial Update: Vigileo FloTrac vs Pulmonary Artery Catheter
This document provides an update on a clinical trial comparing Vigileo FloTrac hemodynamic monitoring with the Pulmonary Artery Catheter. It…
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CLINICAL_TRIALS safety_alert · 2007-09-20Clinical Trial Update: Pergolide Treatment and Valvular Heart Disease
A completed clinical trial evaluating pergolide treatment in patients with valvular heart disease and Parkinson's disease has been reported;…
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CLINICAL_TRIALS trial_result · 2007-09-17Clinical Trial Update: Methods Study to Evaluate Use of Cardiac Ultrasound to Assess Heart Valve Abnormality in People.
Pfizer-sponsored methods study evaluating the use of cardiac ultrasound to assess heart valve abnormalities; the trial status is completed.
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FDA approval · 2007-07-11FDA Approved: WARFARIN SODIUM — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for Warfarin Sodium from Teva Pharmaceuticals USA, Inc. for the generic product under the ANDA.
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CLINICAL_TRIALS research · 2007-06-11Clinical Trial Update: Modeling Genotype and Other Factors to Enhance the Safety of Coumadin Prescribing [NA]
This clinical trial update discusses modeling genotype and other factors to improve the safety of warfarin (Coumadin) prescribing. It covers…