Valvular Heart Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Freestyle-Perimount Calcification Comparison
Completed clinical trial comparing calcification between Freestyle and Perimount aortic valve bioprostheses.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Artificial Intelligence-enhanced Electrocardiogram Diagnoses and Predicts Future Regurgitant Valvular Heart Diseases
This completed clinical trial evaluated an AI-enhanced electrocardiogram for diagnosing valvular heart disease and predicting future regurgi…
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: Echocardiography as Risk-Assessment for Major Adverse Cardiac Events in Major Vascular Surgery Patients
A completed clinical trial evaluated echocardiography as a risk-assessment tool for major adverse cardiac events in patients undergoing majo…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: BIOVALVE - I / II Clincial Investigation [NA]
This document reports a completed BIOVALVE I/II clinical investigation sponsored by Biotronik AG. The study evaluated valvular heart disease…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: SATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation [NA]
Clinical trial update for InnovHeart's SATURN transcatheter mitral valve replacement addressing functional mitral regurgitation. The current…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: 18F-Fluoride Assessment of Aortic Bioprosthesis Durability and Outcome [NA]
A completed clinical trial evaluating 18F-Fluoride imaging to assess the durability and outcomes of aortic bioprosthetic heart valves.
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CLINICAL_TRIALS trial_result · 2024-03-21Clinical Trial Update: Sugammadex Titration in Cardiac Surgery Patients [Phase 4]
A Phase 4 clinical trial updating sugammadex titration in cardiac surgery patients has completed with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Topical Effect of Tranexamic Acid in Postoperative Bleeding and Blood Products Transfusion After Cardiac Surgery [Phase 4]
Phase 4 trial update studying topical tranexamic acid to reduce postoperative bleeding and blood product transfusion after cardiac surgery i…
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: RIvaroxaban for Valvular Heart diseasE and atRial Fibrillation Trial -RIVER Trial [Phase 2]
Phase 2 trial update for rivaroxaban in valvular heart disease with atrial fibrillation (RIVER trial) has completed.
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CLINICAL_TRIALS trial_result · 2021-10-21Clinical Trial Update: A Trial to Evaluate the Effect of Rosuvastatin on Inflammation in Patients Undergoing Isolated Cardiac Valve Surgery [Phase 3]
Phase 3 trial assessing rosuvastatin's effect on inflammation in patients undergoing isolated valvular cardiac surgery has completed.
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CLINICAL_TRIALS trial_result · 2021-10-13Clinical Trial Update: Pre-operative Rehabilitation for Reduction of Hospitalization After Coronary Bypass and Valvular Surgery. [NA]
A clinical trial evaluated a pre-operative rehabilitation program aimed at reducing hospitalization for patients awaiting coronary artery by…
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CLINICAL_TRIALS trial_result · 2021-09-22Clinical Trial Update: Different Modalities of Analgesia in Open Heart Surgeries in Mansoura University [Phase 4]
Phase 4 clinical trial updating analgesia modalities in open-heart surgery patients.
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CLINICAL_TRIALS trial_result · 2021-01-13Clinical Trial Update: Dabigatran Versus Conventional Treatment for Prevention of Silent Cerebral Infarct in Atrial Fibrillation Associated With Valvular Disease [Phase 4]
Phase 4 trial comparing dabigatran to conventional treatment for preventing silent cerebral infarcts in patients with atrial fibrillation an…
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CLINICAL_TRIALS trial_result · 2020-03-26Clinical Trial Update: The Impact of Vitamin C on Postoperative Acute Kidney Injury in Risk Patients Undergoing Valvular Heart Surgery [Phase 4]
Phase 4 clinical trial evaluating the impact of vitamin C on postoperative acute kidney injury in high-risk patients undergoing valvular hea…
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CLINICAL_TRIALS trial_result · 2020-03-24Clinical Trial Update: Hypertonic Saline for Fluid Resuscitation After Cardiac Surgery [Phase 4]
A Phase 4 clinical trial evaluating hypertonic saline for fluid resuscitation after cardiac surgery has completed.
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: Role of High Mobility Group Box 1 as a Prognostic Biomarker in Patients Undergoing Valvular Heart Surgery
Completed clinical trial evaluating high mobility group box 1 (HMGB1) as a prognostic biomarker in patients undergoing valvular heart surger…
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: The Effect of Remote Ischemic Postconditioning on Postoperative Renal Dysfunction in Patients Undergoing Valvular Heart Surgery [NA]
A completed clinical trial evaluating whether remote ischemic postconditioning can reduce postoperative renal dysfunction in patients underg…
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: ADVANCE Direct Aortic Study
Completed clinical trial update for the ADVANCE Direct Aortic study; results posted in 2018 for aortic stenosis and valvular heart disease.
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: CoreValve Advance-II Study: Prospective International Post-market Study
Prospective international post-market study (CoreValve Advance-II) completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Text Message Intervention to Improve Cardiac Rehab Participation [NA]
This entry reports a terminated clinical trial evaluating a text message intervention to boost participation in cardiac rehabilitation.
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CLINICAL_TRIALS trial_result · 2018-05-08Clinical Trial Update: Changes in the Tricuspid Valve Complex Induced by Mitral Valve Annuloplasty
A clinical trial investigated how mitral valve annuloplasty affects the tricuspid valve complex; the study has been terminated.
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: NeoChord TACT Post-Market Surveillance Registry
This entry reports the completed status and posted results of the NeoChord TACT post-market surveillance registry for mitral valve insuffici…
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CLINICAL_TRIALS trial_result · 2018-01-18Clinical Trial Update: Effect of Anesthetics on CD39 and CD73 After Open-heart Surgery [Phase 4]
Phase 4 trial updating the effects of anesthetics on CD39 and CD73 after open-heart surgery for valvular and aortic disease (completed).
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Effects of Prophylactic Desmopressin on Blood Coagulation Parameters in Heart Valve Surgery [Phase 4]
Phase 4 clinical trial evaluating the effects of prophylactic desmopressin on blood coagulation parameters in patients undergoing heart valv…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal Echocardiography [Phase 4]
Phase 4 trial comparing dexmedetomidine and ketofol for sedation during trans-esophageal echocardiography has completed.