Uterine Fibroids
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-09-23Clinical Trial Update: Efficacy of Tranexamic Acid in Reducing Myomectomy Associated Blood Loss in Federal Teaching Hospital Abakaliki. [Phase 2]
Phase 2 trial assessing whether tranexamic acid reduces blood loss during myomectomy; study completed.
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EMA withdrawal · 2020-09-04PRAC recommends revoking marketing authorisation of ulipristal acetate for uterine fibroids
The European Medicines Agency's PRAC recommended revoking the marketing authorisation of ulipristal acetate for treating uterine fibroids du…
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CLINICAL_TRIALS trial_result · 2020-07-21Clinical Trial Update: Safety and Efficacy in Premenopausal Women With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF) [Phase 2]
Phase 2 clinical trial assessing safety and efficacy in premenopausal women with heavy menstrual bleeding associated with uterine fibroids; …
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CLINICAL_TRIALS trial_result · 2020-07-15Clinical Trial Update: Safety and Efficacy of Elagolix in Pre-Menopausal Women With Heavy Uterine Bleeding and Uterine Fibroids [Phase 2]
Phase 2 trial assessing safety and efficacy of elagolix in pre-menopausal women with heavy uterine bleeding and uterine fibroids has complet…
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CLINICAL_TRIALS trial_result · 2020-06-30Clinical Trial Update: An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids [Phase 3]
An extension study evaluating the efficacy and safety of elagolix in premenopausal women with heavy menstrual bleeding due to uterine fibroi…
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CLINICAL_TRIALS trial_result · 2020-06-30Clinical Trial Update: Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study) [Phase 3]
Phase 3 trial evaluating elagolix with estradiol/norethindrone acetate for heavy menstrual bleeding due to uterine fibroids; results posted …
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CLINICAL_TRIALS trial_result · 2020-06-29Clinical Trial Update: Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women [Phase 3]
Phase 3 trial update on elagolix combined with estradiol/norethindrone acetate for heavy menstrual bleeding associated with uterine fibroids…
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FDA approval · 2020-05-29FDA Approved: ORIAHNN — Original Application (AbbVie Inc.)
FDA approved ORIAHNN, a fixed-dose combination of elagolix, estradiol, and norethindrone, from AbbVie in an Original Application, for the tr…
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CLINICAL_TRIALS trial_result · 2020-04-28Clinical Trial Update: Intravenous Oxytocin Versus Tranexamic Acid in Reducing Blood Loss During Abdominal Myomectomy. [Phase 4]
A Phase 4 clinical trial comparing intravenous oxytocin to tranexamic acid for reducing blood loss during abdominal myomectomy has completed…
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CLINICAL_TRIALS trial_result · 2020-04-28Clinical Trial Update: Endometrial Preparation by Short Course of Letrozole Before Hysteroscopic Removal of Endocavitary Lesions [Phase 4]
Phase 4 clinical trial investigating endometrial preparation with a short course of letrozole prior to hysteroscopic removal of endocavitary…
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CLINICAL_TRIALS trial_result · 2020-04-13Clinical Trial Update: Ulipristal Acetate in Symptomatic Uterine Fibroid [Phase 4]
Phase 4 trial update for ulipristal acetate in symptomatic uterine fibroids has been terminated.
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EMA safety_alert · 2020-03-13Suspension of ulipristal acetate for uterine fibroids during ongoing EMA review of liver injury risk
EMA suspended Ulipristal acetate for uterine fibroids while reviewing risk of severe liver injury.
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CLINICAL_TRIALS withdrawal · 2020-01-18Clinical Trial Update: Assessment of Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids [Phase 3]
Phase 3 trial assessing vilaprisan for uterine fibroids has been withdrawn.
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Treatment of Uterine Fibroids With CDB-2914, an Experimental Selective Progesterone Receptor Antagonist [Phase 2]
Phase 2 trial update for CDB-2914 (a selective progesterone receptor antagonist) in treating uterine fibroids (leiomyoma) completed.
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CLINICAL_TRIALS trial_result · 2019-09-20Clinical Trial Update: Evaluation of Uterine Patency Following Sonography-guided Transcervical Ablation of Fibroids
A completed clinical trial evaluated uterine patency after sonography-guided transcervical ablation of fibroids, with results posted in 2019…
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CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: Preoperative Vaginal Dinoprostone Prior to Abdominal Myomectomy [Phase 3]
Phase 3 clinical trial investigating preoperative vaginal dinoprostone before abdominal myomectomy.
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CLINICAL_TRIALS trial_result · 2019-09-04Clinical Trial Update: PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata [Phase 3]
Phase 3 trial update for PGL4001 evaluating efficacy in reducing symptoms of uterine fibroids has completed with results posted.
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FDA approval · 2019-08-28FDA Approved: ORILISSA — Supplemental Application (AbbVie Inc.)
The FDA approved a supplemental application for ORILISSA (elagolix) submitted by AbbVie, likely updating labeling and/or indications based o…
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CLINICAL_TRIALS trial_result · 2019-08-07Clinical Trial Update: A Study on the Mifepristone Tablets in the Treatment of Symptomatic Uterine Fibroids With Safety and Efficacy [Phase 4]
Phase 4 trial update for mifepristone tablets in symptomatic uterine fibroids; study terminated.
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CLINICAL_TRIALS trial_result · 2019-08-05Clinical Trial Update: Superior Hypogastric Nerve Block for Pain Control Post-uterine Fibroid Embolization [Phase 2]
A Phase 2 clinical trial evaluated superior hypogastric nerve block to manage pain after uterine fibroid embolization; results completed wit…
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CLINICAL_TRIALS trial_result · 2019-06-19Clinical Trial Update: A Multi-Center, Parallel Design, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 6 and 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids [Phase 2]
Phase 2 randomized trial evaluating safety and efficacy of 6 mg and 12 mg Telapristone Acetate (Proellex) in premenopausal women with sympto…
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CLINICAL_TRIALS trial_result · 2019-06-19Clinical Trial Update: An Extension Study of 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids [Phase 2]
Phase 2 extension study of 12 mg Proellex (telapristone acetate) in premenopausal women with symptomatic uterine fibroids; study terminated …
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CLINICAL_TRIALS trial_result · 2019-06-14Clinical Trial Update: Safety and Efficacy of Telapristone Acetate (Proellex®) Administered Vaginally for the Treatment of Uterine Fibroids [Phase 2]
Phase 2 trial evaluating safety and efficacy of vaginal telapristone acetate (Proellex) for uterine fibroids has completed with results post…
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CLINICAL_TRIALS trial_result · 2019-06-12Clinical Trial Update: Magnetic Resonance (MR) Guided Focused Ultrasound Surgery of Uterine Fibroids [NA]
Completed clinical trial evaluating MR-guided focused ultrasound surgery for uterine fibroids (leiomyoma) with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-22Clinical Trial Update: A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids [Phase 3]
A Phase 3 placebo-controlled trial evaluating relugolix (TAK-385) 40 mg for pain symptoms due to uterine fibroids has completed; results wer…