Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS other · 2026-01-12Clinical Trial Update: A Study of Adjuvant Cretostimogene Grenadenorepvec for Treatment of Intermediate Risk NMIBC Following TURBT [Phase 3]
Phase 3 trial evaluating adjuvant Cretostimogene Grenadanorepvec for intermediate-risk non-muscle invasive bladder cancer after TURBT is cur…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: 18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy [EARLY_Phase 1]
An early-phase trial update reports results for using 18F-fluciclovine PET/CT to stage muscle-invasive bladder cancer before radical cystect…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Pemetrexed and Avelumab in Treating Patients With MTAP-Deficient Metastatic Urothelial Cancer [Phase 2]
Phase 2 clinical trial evaluating pemetrexed in combination with avelumab for MTAP-deficient metastatic urothelial carcinoma; currently acti…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice
This clinical trial update reports on real-world outcomes and safety of atezolizumab in routine practice. It includes patients with urotheli…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Renal Retention in High Grade Upper Tract Urothelial Cancer [Phase 2]
A Phase 2 clinical trial at Johns Hopkins is recruiting to evaluate treatment for high-grade upper tract urothelial carcinoma and bladder ca…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer [Phase 1, Phase 2]
Update on a Phase II study evaluating Atezolizumab with cisplatin and gemcitabine as neoadjuvant therapy for bladder cancer; the trial is cu…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Neoadjuvant Toripalimab in Combination With Gemcitabine Therapy in Cisplatin Ineligible Local Advanved Bladder Cancer [Phase 2]
Phase 2 neoadjuvant trial of toripalimab in combination with gemcitabine for cisplatin-ineligible locally advanced urothelial carcinoma/blad…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: 9MW2821 Combined With Toripalimab in Perioperative Patients With Urothelial Cancer [Phase 2]
Phase 2 clinical trial of 9MW2821 in combination with toripalimab for perioperative urothelial carcinoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Futibatinib and Pembrolizumab Combination in the Treatment of Advanced or Metastatic Urothelial Carcinoma [Phase 2]
Phase 2 study evaluating the combination of futibatinib and pembrolizumab for advanced or metastatic urothelial carcinoma was terminated, wi…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Adjuvant Radioimmunotherapy Compared With Adjuvant Chemotherapy for UTUC
Recruitment is ongoing for a study comparing adjuvant radioimmunotherapy versus adjuvant chemotherapy in patients with upper tract urothelia…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Identification of Novel High Quality Methylated DNA Markers in Renal Tumors: Whole Methylome Discovery, Tissue Validation, and Feasibility Testing In Blood and Urine, The INQUIRE Study
A Mayo Clinic-led INQUIRE study is identifying novel high-quality methylated DNA markers for renal tumors. The project uses whole-methylome …
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Zanzalintinib for Advanced Urothelial Carcinoma Progressing After Prior Therapy [Phase 2]
Phase 2 trial of zanzalintinib for advanced urothelial carcinoma progressing after prior therapy is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) [Phase 2]
Phase II trial evaluating trastuzumab deruxtecan (Trastuzumab Rezetecan) alone or in combination with Adebrelimab for HER2-expressing locall…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of INBRX-106 in combination with pembrolizumab for locally advanced or metastatic sol…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Combination of Ipi/Nivo Plus Sacituzumab Govitecan in Metastatic Cisplatin Ineligible Urothelial Carcinoma Patients [Phase 1, Phase 2]
A Phase 1/2 trial is evaluating the combination of ipilimumab, nivolumab, and sacituzumab govitecan in metastatic cisplatin-ineligible uroth…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A Study to Compare the Results of FGFR Testing by Either ctDNA Blood Testing or Standard Tumor Tissue Testing
A clinical study comparing FGFR testing results obtained from ctDNA blood testing to standard tumor tissue testing in metastatic bladder can…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Evolution of Proteomic Profiles of Intestinal Microbiota in Patients With Locally Advanced or Metastatic Urothelial Carcinomas
This clinical trial update reports on the evolution of proteomic profiles of the intestinal microbiota in patients with locally advanced or …
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program [Phase 2]
Phase 2 trial evaluating in-home versus in-clinic subcutaneous nivolumab administration under the CC Beyond Walls program; the study is curr…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma [Phase 2]
Phase 2 clinical trial evaluating consolidative local therapy for oligometastatic urothelial carcinoma, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC [Phase 1]
Phase 1 clinical trial evaluating intravesical adoptive cell therapy using tumor-infiltrating lymphocytes (TIL) for BCG-exposed high-grade n…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Combination of Avelumab and Taxane (AVETAX) for Urothelial Cancer [Phase 1]
This clinical trial update reports on a Phase 1 study evaluating the combination of avelumab with a taxane for urothelial carcinoma, which h…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer. [Phase 1]
Phase 1 trial update of Naptumomab Estafenatox in combination with durvalumab in selected advanced or metastatic solid tumors, including eso…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC [Phase 1]
Phase 1 trial evaluating LB-LR1109 alone and in combination with atezolizumab for solid tumors, including non-small cell lung cancer, curren…
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FDA approval · 2025-11-21FDA Approved: PADCEV EJFV — Supplemental Application (SEAGEN INC.)
The FDA approved a supplemental application for PADCEV EJFV (enfortumab vedotin) filed by Seagen Inc., resulting in an updated labeling for …
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?
A recruiting clinical trial in women with isolated acute cystitis and macroscopic hematuria to evaluate the need for further investigation o…