Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: CLE Characteristics of Upper Urinary Tract Urothelial Carcinoma
The clinical trial investigating CLE characteristics of upper urinary tract urothelial carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2018-04-24Clinical Trial Update: Phase II Trial of Palbociclib in Patients With Metastatic Urothelial Cancer After Failure of First-Line Chemotherapy [Phase 2]
Phase II trial of palbociclib in metastatic urothelial carcinoma after failure of first-line chemotherapy was terminated; results posted in …
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211] [Phase 3]
Phase 3 trial comparing atezolizumab with chemotherapy in locally advanced or metastatic urothelial bladder cancer has completed; results po…
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CLINICAL_TRIALS trial_result · 2018-03-15Clinical Trial Update: A Phase I/II Trial of AEZS-108 in Urothelial Cancer Patients Who Failed Platinum-chemotherapy [Phase 1, Phase 2]
The trial update notes termination of the Phase I/II study of AEZS-108 in urothelial carcinoma patients who failed platinum-based chemothera…
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CLINICAL_TRIALS trial_result · 2018-02-27Clinical Trial Update: A Study Evaluating MM-310 in Patients With Solid Tumors [Phase 1]
This update reports a Phase 1 study evaluating MM-310 in patients with solid tumors. The listed indications include urothelial carcinoma, ga…
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CLINICAL_TRIALS trial_result · 2017-12-22Clinical Trial Update: The Effectiveness and Safety of Intravesical Docetaxel Instillation for Prevent Bladder Recurrence [Phase 2]
Phase 2 clinical trial assessing the effectiveness and safety of intravesical docetaxel instillation to prevent bladder recurrence in urothe…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Phase 2 Study of Docetaxel +/- OGX-427 in Patients With Relapsed or Refractory Metastatic Bladder Cancer [Phase 2]
Phase 2 trial evaluating docetaxel with or without OGX-427 in relapsed/refractory metastatic bladder cancer; study completed with posted res…
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: Study of Mocetinostat in Patients With Urothelial Carcinoma Having Inactivating Alterations of Specific Genes [Phase 2]
The document reports completion of a Phase 2 study evaluating Mocetinostat in patients with urothelial carcinoma who have inactivating alter…
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CLINICAL_TRIALS trial_result · 2017-08-09Clinical Trial Update: Cabazitaxel in Patients With Urothelial Carcinoma Who Have Disease Progression Following Platinum-Based Chemotherapy [Phase 2]
Phase 2 study of cabazitaxel in urothelial carcinoma patients after platinum-based chemotherapy has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Trial of Adjuvant Sutent for Patients With High Risk Urothelial Carcinoma After Neoadjuvant Chemotherapy and Cystectomy [Phase 2]
A Phase 2 trial evaluating adjuvant sunitinib (Sutent) after cystectomy for high-risk urothelial carcinoma of the bladder was terminated, wi…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: Ph 1B B-701 in Combination With Pembrolizumab in Metastatic Transitional Cell Carcinoma of the Urothelial Tract [Phase 1]
This clinical trial update reports termination of a Phase 1B study of B-701 in combination with pembrolizumab for metastatic bladder/urothel…
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CLINICAL_TRIALS trial_result · 2017-06-21Clinical Trial Update: Pemetrexed Maintenance in Patients With Urothelial Carcinoma Who Completed First Line Platinum-based Chemotherapy [Phase 3]
Phase 3 trial evaluating pemetrexed maintenance therapy in patients with urothelial carcinoma who completed first-line platinum-based chemot…
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: DN24-02 as Adjuvant Therapy in Subjects With High Risk HER2+ Urothelial Carcinoma [Phase 2]
Phase 2 trial DN24-02 as adjuvant therapy for high-risk HER2-positive urothelial carcinoma was terminated; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-06Clinical Trial Update: Efficacy of Combination of Trastuzumab to Gemcitabine - Platinum Advanced or Metastatic Urothelial Carcinoma [Phase 2]
Phase 2 trial update evaluating the combination of trastuzumab with gemcitabine and platinum chemotherapy in patients with advanced or metas…
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CLINICAL_TRIALS trial_result · 2016-12-02Clinical Trial Update: Phase I Study of Vorinostat in Combination With Docetaxel in Patients With Advanced and Relapsed Solid Malignancies. [Phase 1]
This Phase I trial evaluated vorinostat in combination with docetaxel in patients with advanced and relapsed solid malignancies, including n…
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CLINICAL_TRIALS approval · 2016-11-02Clinical Trial Update: An Expanded Access Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Carcinoma After Failure With Platinum-Containing Chemotherapy
Expanded-access update for atezolizumab in locally advanced or metastatic urothelial carcinoma after platinum-containing chemotherapy, with …
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Study of Neoadjuvant Ipilimumab in Patients With Urothelial Carcinoma Undergoing Surgical Resection [Phase 1]
This document reports the completion of a Phase 1 trial evaluating neoadjuvant ipilimumab in patients with urothelial carcinoma undergoing s…
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FDA approval · 2016-05-18FDA Approved: TECENTRIQ — Original Application (Genentech, Inc.)
This FDA page documents the original Biologics License Application approval of Tecentriq (atezolizumab) from Genentech, marking the first FD…
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: Phase I Study of Percutaneous Valrubicin for Upper Tract Urothelial Carcinoma [Phase 1]
Phase I study of percutaneous valrubicin for upper tract urothelial carcinoma has completed its Phase I evaluation. The trial status is COMP…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: A Study of BIND-014 in Patients With Urothelial Carcinoma, Cholangiocarcinoma, Cervical Cancer and Squamous Cell Carcinoma of the Head and Neck [Phase 2]
A Phase 2 study of BIND-014 across urothelial carcinoma, cholangiocarcinoma, cervical cancer, and squamous cell carcinoma of the head and ne…
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Phase II Trial of Gemcitabine, Carboplatin, and Bevacizumab in Chemotherapy Naive Patients With Advanced/Metastatic Urothelial Carcinoma [Phase 2]
Phase II trial update reporting results from gemcitabine, carboplatin, and bevacizumab in chemotherapy-naive patients with advanced or metas…
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CLINICAL_TRIALS trial_result · 2015-12-24Clinical Trial Update: Trial of Amrubicin as Second-Line Therapy in Patients With Advanced/Metastatic Refractory Urothelial Carcinoma [Phase 2]
Amrubicin was tested as a second-line therapy in advanced/metastatic refractory urothelial carcinoma in a Phase 2 trial; the study was termi…
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CLINICAL_TRIALS trial_result · 2015-10-06Clinical Trial Update: Iressa and Taxotere Study in Patients With Metastatic Urothelial Cancer [Phase 2]
Phase 2 trial evaluating gefitinib (Iressa) in combination with docetaxel (Taxotere) for metastatic urothelial cancer (bladder cancer) was t…
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CLINICAL_TRIALS withdrawal · 2015-08-19Clinical Trial Update: Second-Line Docetaxel + ASA404 for Advanced Urothelial Carcinoma [Phase 2]
Withdrawn Phase 2 trial evaluating second-line docetaxel plus ASA-404 for advanced urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: A Trial of Cabazitaxel for Advanced Transitional Cell Carcinoma (TCC) [Phase 2]
Completed Phase 2 clinical trial evaluating cabazitaxel for advanced urothelial carcinoma (transitional cell carcinoma).