Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-05-23Clinical Trial Update: Maintenance With Niraparib In Patients With Advanced Urothelial Cancer After 1st-line Platinum-based Chemotherapy [Phase 2]
Phase 2 trial update evaluating maintenance niraparib in advanced urothelial cancer after first-line platinum-based chemotherapy has complet…
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CLINICAL_TRIALS trial_result · 2022-04-14Clinical Trial Update: The Effectiveness and Safety of Intravesical Gemcitabine Instillation to Prevent Intravesical Recurrence [Phase 2]
Phase 2 clinical trial update evaluating intravesical gemcitabine to prevent recurrence in urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2022-04-08Clinical Trial Update: A Study of Trastuzumab and Pyrotinib in HER2 Positive Locally Advanced or Metastatic Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating trastuzumab plus pyrotinib for HER2-positive urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2022-03-22Clinical Trial Update: A Phase II Study of Bintrafusp Alfa (M7824) in Checkpoint Inhibitor Naive and Refractory Subjects With Urothelial Carcinoma [Phase 2]
Phase II study of Bintrafusp Alfa (M7824) in urothelial cancer has been terminated with posted results.
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: A Prospective Study of Neoadjuvant Chemotherapy With Gemcitabine/Platinum in Muscle-Invasive or Locally-Advanced Urothelial Carcinoma of Bladder [Phase 2]
Phase 2 study evaluating neoadjuvant gemcitabine/platinum chemotherapy for muscle-invasive or locally-advanced urothelial carcinoma of the b…
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: Study of Tipifarnib in Patients With Previously-Treated, Advanced, HRAS Mutant Urothelial Carcinoma [Phase 2]
Phase 2 clinical trial update for tipifarnib in previously treated, advanced HRAS-mutant urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2022-02-18Clinical Trial Update: Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma [Phase 2]
Phase 2 study update on neoadjuvant dose-dense MVAC therapy for muscle-invasive bladder cancer and locally advanced urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2022-01-13Clinical Trial Update: Nab-paclitaxel Plus Gemcitabine as First-line Therapy for Cisplatin-ineligible or Cisplatin-incurable Advanced Urothelial Carcinoma [Phase 2]
Phase 2 trial of nab-paclitaxel plus gemcitabine as first-line therapy for cisplatin-ineligible or cisplatin-incurable advanced urothelial c…
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CLINICAL_TRIALS trial_result · 2021-12-29Clinical Trial Update: Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma [Phase 2, Phase 3]
Phase 2/3 study evaluating rografatinib (BAY1163877) versus chemotherapy in FGFR-positive urothelial carcinoma; the trial is completed with …
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CLINICAL_TRIALS trial_result · 2021-12-17Clinical Trial Update: A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer [Phase 2]
Phase 2 study of enfortumab vedotin in locally advanced or metastatic urothelial cancer has been completed and results have been posted. The…
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CLINICAL_TRIALS trial_result · 2021-12-15Clinical Trial Update: Anti-PD(L)1 and SBRT in the Treatment of Advanced, Platinum-Refractory Urothelial Carcinoma [Phase 2]
Phase 2 trial investigating anti-PD(L)1 therapy combined with SBRT in advanced, platinum-refractory urothelial carcinoma; study is terminate…
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CLINICAL_TRIALS trial_result · 2021-12-14Clinical Trial Update: A Study of MRG002 in the Treatment of HER2-positive Unresectable Locally Advanced or Metastatic Urothelium Cancer [Phase 2]
Phase 2 trial update for MRG002 in HER2-positive unresectable locally advanced or metastatic urothelial cancer.
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CLINICAL_TRIALS trial_result · 2021-12-13Clinical Trial Update: A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors [Phase 1]
A Phase 1 dose-escalation study of PF-06801591 in multiple solid tumors including melanoma, head and neck cancer, ovarian cancer, sarcoma, n…
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CLINICAL_TRIALS trial_result · 2021-11-23Clinical Trial Update: Study Comparing Denosumab With Standard Treatment in Urothelial Cancer Patients With Bone Metastases [Phase 2]
Phase 2 trial comparing denosumab with standard treatment in urothelial cancer patients with bone metastases has completed.
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CLINICAL_TRIALS trial_result · 2021-11-04Clinical Trial Update: Atezolizumab + Guadecitabine in Patients With Checkpoint Inhibitor Refractory or Resistant Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating atezolizumab plus guadecitabine in patients with checkpoint inhibitor refractory or resistant urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2021-10-21Clinical Trial Update: A Phase 1b/2 Clinical Study to Evaluate the Safety and Tolerability and Efficacy of AZD4547 [Phase 1, Phase 2]
Phase 1b/2 trial evaluating safety, tolerability, and efficacy of AZD4547 in urothelial carcinoma is in early stages with unknown status.
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CLINICAL_TRIALS trial_result · 2021-09-22Clinical Trial Update: A Phase II Randomized Trial of Immunotherapy Plus Radiotherapy in Metastatic Genitourinary Cancers [Phase 2]
Phase II randomized trial assessing immunotherapy plus radiotherapy in metastatic genitourinary cancers; study terminated with results poste…
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CLINICAL_TRIALS trial_result · 2021-09-01Clinical Trial Update: Anlotinib Combined With Platinum/Gemcitabine for First Line Treatment of Advanced Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating anlotinib in combination with platinum/gemcitabine for first-line advanced urothelial carcinoma is ongoing, with st…
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CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: Phase 2 Trial of Nab-paclitaxel Plus S-1 vs Gemcitabine Plus Cisplatin as 1-line Chemotherapy of Patients With Local Advanced and/or Metastatic Transitional Cell Carcinoma of Urothelial Tract [Phase 2]
A phase 2 trial comparing nab-paclitaxel plus S-1 versus gemcitabine plus cisplatin as first-line therapy for locally advanced or metastatic…
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CLINICAL_TRIALS trial_result · 2021-05-20Clinical Trial Update: Study of Pembrolizumab With or Without Platinum-based Combination Chemotherapy Versus Chemotherapy Alone in Urothelial Carcinoma (MK-3475-361/KEYNOTE-361) [Phase 3]
Phase 3 trial evaluating pembrolizumab with or without platinum-based chemotherapy versus chemotherapy alone in urothelial carcinoma complet…
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CLINICAL_TRIALS trial_result · 2021-05-20Clinical Trial Update: Pemetrexed Disodium in Treating Patients With Previously Treated Metastatic Urothelial Cancer [Phase 2]
Phase 2 clinical trial of pemetrexed disodium in previously treated metastatic urothelial carcinoma was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: Study of MEDI4736 (Durvalumab) With or Without Tremelimumab Versus Standard of Care Chemotherapy in Urothelial Cancer [Phase 3]
Phase 3 study evaluating durvalumab with or without tremelimumab versus standard-of-care chemotherapy in urothelial carcinoma; results were …
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CLINICAL_TRIALS trial_result · 2021-03-09Clinical Trial Update: I-MVAC +/- Panitumumab as First-line Treatment of Advanced Urothelial Carcinoma Without H-Ras Nor K-Ras Mutations [Phase 3]
A phase 3 trial evaluating I-MVAC with or without panitumumab as first-line therapy for advanced urothelial carcinoma without KRAS or HRAS m…
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: A Phase 2, Single-Center, Open Label Study of Autologous, Adoptive Cell Therapy Following a Reduced Intensity, Non-myeloablative, Lymphodepleting Induction Regimen in Metastatic Urothelial Carcinoma Patients [Phase 2]
Phase 2, single-center study evaluating autologous adoptive cell therapy after a lymphodepleting regimen in metastatic urothelial carcinoma;…
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Neoadjuvant PD-1 Monoclonal Antibody Plus Cisplatin-based Chemotherapy in Locally Advanced Upper Tract Urothelial Carcinoma [Phase 2]
Phase 2 trial updating neoadjuvant PD-1 monoclonal antibody plus cisplatin-based chemotherapy for locally advanced upper tract urothelial ca…