Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Trial of Tremelimumab in Patients With Previously Treated Metastatic Urothelial Cancer [Phase 2]
Phase 2 trial of tremelimumab in previously treated metastatic urothelial cancer has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer [Phase 3]
A Phase 3 study of UGN-102 for low-grade intermediate-risk non-muscle invasive bladder cancer was terminated, with results posted on 2024-06…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: A Study of Pembrolizumab+ sEphB4 in Metastatic Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating pembrolizumab in combination with sEphB4 for metastatic urothelial carcinoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: KHK2455 (IDO Inhibitor) Plus Avelumab in Adult Subjects With Advanced Bladder Cancer [Phase 1]
Phase 1 study of KHK2455 (IDO inhibitor) plus Avelumab in adults with advanced urothelial carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: A Study of DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial of DSP-7888 Dosing Emulsion in combination with immune checkpoint inhibitors in adults with advanced solid tumors was termin…
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CLINICAL_TRIALS trial_result · 2024-04-04Clinical Trial Update: A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract [Phase 3]
Phase 3 trial of atezolizumab in locally advanced or metastatic urothelial or non-urothelial carcinoma of the urinary tract has completed wi…
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: A Study of TAS-120 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of futibatinib (TAS-120) in patients with advanced solid tumors, including cholangiocarcinoma, urothelial carcinoma, breas…
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CLINICAL_TRIALS trial_result · 2024-03-18Clinical Trial Update: Checkpoint Inhibition and Chemoradiotherapy as Bladder Sparing Treatment in UC [Phase 2]
Phase 2 trial evaluating checkpoint inhibition with chemoradiotherapy as a bladder-sparing approach for urothelial carcinoma of the bladder.
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A safety and tolerability study of NC318 in advanced or metastatic solid tumors completed Phase 1/2 with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-03-01Clinical Trial Update: A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma [Phase 2]
This Phase 2 trial evaluating NIR178 in combination with PDR001 across multiple solid tumors and non-Hodgkin lymphoma was terminated, with r…
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CLINICAL_TRIALS trial_result · 2024-01-24Clinical Trial Update: Safety and Efficacy of TT-00420 Tablets Combined With Toripalimab Injection in Advanced Urological Tumors [Phase 1, Phase 2]
Clinical trial update on TT-00420 tablets with toripalimab for advanced urological tumors (Phase 1/2) with conditions including clear cell r…
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: CHEckpoint Inhibition in Combination With an Immunoboost of External Beam Radiotherapy in Solid Tumors [Phase 2]
Phase 2 trial evaluating checkpoint inhibition in combination with external beam radiotherapy for solid tumors; study is completed.
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: A Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Participants With a Solid Tumor (SEASTAR) [Phase 1, Phase 2]
Phase 1/2 trial SEASTAR evaluating rucaparib in combination with other anticancer agents in solid tumors; study terminated with results post…
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: Neoadjuvant PD-1 Monoclonal Antibody in Cisplatin-ineligible High Risk Upper Tract Urothelial Carcinoma [Phase 2]
A Phase 2 trial evaluating a neoadjuvant PD-1 monoclonal antibody in cisplatin-ineligible high-risk upper urinary tract urothelial carcinoma…
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CLINICAL_TRIALS trial_result · 2023-12-21Clinical Trial Update: A Study of RC48-ADC Combined With Cadonilimab（AK104）in the Treatment of HER2-expression Locally Advanced or Metastatic Urothelial Carcinoma [Phase 2]
A Phase 2 trial evaluating RC48-ADC in combination with Cadonilimab (AK104) for HER2-expressing locally advanced or metastatic urothelial ca…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: A Study of RC48-ADC Combined With Toripalimab For First-line Treatment of Urothelial Carcinoma [Phase 3]
Phase 3 trial evaluating RC48-ADC plus toripalimab for first-line urothelial carcinoma (HER2-expressing). Status: recruiting.
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: A Study of RC48-ADC in Subjects With HER2-negative Locally Advanced or Metastatic Urothelial Cancer [Phase 2]
Phase 2 trial update for RC48-ADC in HER2-negative urothelial cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-12-13Clinical Trial Update: Study of Atezolizumab as Monotherapy and in Combination With Platinum-Based Chemotherapy in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma [Phase 3]
Phase 3 trial evaluating atezolizumab as a standalone therapy and in combination with platinum-based chemotherapy for untreated locally adva…
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CLINICAL_TRIALS trial_result · 2023-11-27Clinical Trial Update: A Open-label, Single-arm, Multicenter, Phase II Study of RC48-ADC to Evaluate the Efficacy and Safety of Subjects With HER2 Overexpressing Locally Advanced or Metastatic Urothelial Cancer [Phase 2]
Phase II open-label trial evaluating RC48-ADC in HER2-overexpressing locally advanced or metastatic urothelial cancer completed.
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: First-line Everolimus +/- Paclitaxel for Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating first-line everolimus with or without paclitaxel in cisplatin-ineligible advanced urothelial carcinoma was terminat…
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Study of First-line Pembrolizumab (MK-3475) With Lenvatinib (MK-7902/E7080) in Urothelial Carcinoma Cisplatin-ineligible Participants Whose Tumors Express Programmed Cell Death-Ligand 1 and in Participants Ineligible for Platinum-containing Chemotherapy (MK-7902-011/E7080-G000-317/ LEAP-011) [Phase 3]
Phase 3 trial evaluating first-line pembrolizumab in combination with lenvatinib for urothelial carcinoma in cisplatin-ineligible or platinu…
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer [Phase 1, Phase 2]
Clinical trial update on erdafitinib in participants with metastatic or locally advanced urothelial carcinoma (Phase 1/2); results have been…
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CLINICAL_TRIALS trial_result · 2023-10-13Clinical Trial Update: Derazantinib and Atezolizumab in Patients With Urothelial Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating derazantinib with atezolizumab in urothelial carcinoma has been completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations [Phase 2]
Phase 2 trial updating activity of molecularly matched targeted therapies across select tumor types based on genomic alterations; study comp…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: A Study of a Personalized Neoantigen Cancer Vaccine [Phase 1, Phase 2]
Clinical trial update for a personalized neoantigen cancer vaccine completed across Phase 1 and Phase 2.