Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Improve Checkpoint-blockade Response in Advanced Urothelial Cancer [Phase 1, Phase 2]
This entry reports the completion of a Phase 1/2 clinical trial investigating strategies to improve response to checkpoint inhibitors in adv…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Pre-operative Immunotherapy in Stage II-III Urothelial Cancer [Phase 1]
Phase 1 study evaluating pre-operative immunotherapy for stage II-III urothelial carcinoma; status is completed.
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Intermittent Checkpoint Inhibitor Therapy In Patients With Advanced Urothelial Carcinoma [Phase 2]
A Phase 2 trial of intermittent checkpoint inhibitor therapy for advanced urothelial carcinoma was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers [Phase 1, Phase 2]
Phase 1/2 trial update evaluating nivolumab plus ABI-009 (nab-rapamycin) in patients with advanced sarcoma and selected cancers, with result…
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial update of LYT-200 as a single agent and in combination with chemotherapy or tislelizumab in locally advanced or met…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: A Study of TAR-200 in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder Who Are Ineligible for or Refuse Cisplatin-based Chemotherapy and Who Are Unfit for Radical Cystectomy [Phase 1]
This is a Phase 1 clinical trial update for TAR-200 in patients with muscle-invasive bladder cancer who are ineligible for cisplatin-based c…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers [Phase 1]
Phase 1 study of cosibelimab (CK-301) as a single-agent therapy in adults with advanced cancers; the trial status is active but not recruiti…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial Cancer [Phase 1]
A Phase 1 study evaluating the combination of trastuzumab deruxtecan with nivolumab in advanced breast cancer and urothelial carcinoma has c…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Abraxane With Anti-PD1/PDL1 in Patients With Advanced Urothelial Cancer [Phase 2]
Phase 2 trial results update on Abraxane combined with an anti-PD1/PDL1 inhibitor in advanced urothelial carcinoma; the study is completed a…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Atezolizumab With Bevacizumab in Previously Untreated Metastatic/Unresectable Urothelial Cancer [Phase 2]
A Phase 2 trial of atezolizumab with bevacizumab in previously untreated metastatic/unresectable urothelial carcinoma was terminated; result…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: A CR-UK Phase I Trial of LY3143921 [Phase 1]
Phase I trial update for LY3143921 sponsored by Cancer Research UK; the study is Active Not Recruiting and explores multiple cancer indicati…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: PSMA Expression and PSMA PET Imaging in Soft Tissue Sarcomas and Urothelial Cell Carcinomas [NA]
A completed clinical trial update examining PSMA expression and PSMA PET imaging in soft tissue sarcomas and urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Chidamide With Immunotherapy for Patients With Locally Advanced or Metastatic Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating chidamide in combination with immunotherapy for locally advanced or metastatic urothelial carcinoma. The study is c…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Cabozantinib Plus Pembrolizumab as First-Line Therapy for Cisplatin-Ineligible Advanced Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating cabozantinib plus pembrolizumab as first-line therapy for cisplatin-ineligible advanced urothelial carcinoma; resul…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Neutron Radiation Therapy and Pembrolizumab in Treating Participants With Advanced Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating neutron radiation therapy with pembrolizumab in advanced urothelial carcinoma; the study is terminated with results…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Association Between Drug-related Cutaneous Adverse Events and Progression Free Survival in Patients Treated with Enfortumab Vedotin
This clinical trial update evaluates whether enfortumab vedotin–associated cutaneous adverse events correlate with progression-free survival…
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer [Phase 3]
Update on a Phase 3 single-arm trial of UGN-102 for low-grade, intermediate-risk non-muscle invasive bladder cancer; results were posted in …
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types [Phase 1]
A Phase 1 study evaluating MT-8421 as monotherapy and in combination with nivolumab in selected advanced solid tumors has been terminated. T…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: A Study of Enfortumab Vedotin in Japanese Subjects With Locally Advanced or Metastatic Urothelial Carcinoma [Phase 1]
Phase 1 study of enfortumab vedotin in Japanese subjects with locally advanced or metastatic urothelial carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC) [Phase 3]
Phase 3 trial update evaluating feasibility of at-home instillation of UGN-102 for low-grade non-muscle invasive bladder cancer. Results wer…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: The Efficacy of the IUrisure for Detection of Recurrent Urothelial Carcinoma
An update on a clinical trial evaluating the efficacy of IUrisure for detecting recurrent urothelial carcinoma; the current status of the tr…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer [Phase 1]
Phase 1 trial evaluating the combination of ramucirumab and pembrolizumab in gastric/GEJ adenocarcinoma, non-small cell lung cancer, urothel…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study of PF-07209960 in advanced or metastatic solid tumors was terminated, with results posted in July 2024.
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Trial of Stereotactic Body Radiotherapy With Concurrent Pembrolizumab in Metastatic Urothelial Cancer [Phase 1]
A Phase 1 trial assessing stereotactic body radiotherapy with concurrent pembrolizumab for metastatic urothelial carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) [Phase 1]
This update reports the completion of a Phase 1 study (DUET-3) evaluating XmAb23104 in patients with selected advanced solid tumors.