Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours [Phase 1, Phase 2]
NuCana plc announced termination of a Phase 1/2 trial evaluating NUC-3373 in combination with other agents for patients with advanced solid …
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial reports on the safety, tolerability, pharmacokinetics, and pharmacodynamics of INCB099280 in participants with advanced s…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the combination of focused ultrasound ablation with PD-1 antibody blockade in advanced solid tumors has been termin…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: INO-5401 + INO-9012 in Combination With Atezolizumab in Locally Advanced Unresectable or Metastatic/Recurrent Urothelial Carcinoma [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase 1/2 study evaluating the combination of INO-5401 and INO-9012 with atezolizumab…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer [Phase 1, Phase 2]
NCI-sponsored trial EP0057 (camptothecin nanoparticle) combined with olaparib in relapsed/refractory small cell lung cancer completed Phase …
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Clofarabine Therapy in Locally Advanced or Metastatic Urothelial Carcinoma [Phase 1, Phase 2]
This entry announces an ongoing Phase 1/2 clinical trial evaluating clo farabine therapy in locally advanced or metastatic urothelial carcin…
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate [Phase 1]
Phase 1 trial evaluating pembrolizumab with chemotherapy for locally advanced or metastatic small cell and neuroendocrine cancers of the uro…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Multicohort Phase II Trial of sEphB4-HSA+Pembrolizumab in Solid Tumors [Phase 2]
This is a Phase II multicohort trial assessing sEphB4-HSA in combination with pembrolizumab for solid tumors; the study is currently active …
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: STRATA: Safe Testing of Risk for AsymptomaTic MicrohematuriA [NA]
A completed trial evaluating a safe testing approach for risk of asymptomatic microscopic hematuria associated with urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors [Phase 1]
Phase 1 dose-escalation study of MNPR-101-PCTA-177Lu in solid tumors is currently recruiting across multiple cancer indications.
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations [Phase 3]
Phase 3 study comparing erdafitinib with vinflunine, docetaxel, or pembrolizumab in advanced urothelial carcinoma with FGFR gene alterations…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Phase 1/2 Study of APR-246 in Combination With Pembrolizumab in Subjects With Solid Tumor Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating APR-246 in combination with pembrolizumab in solid tumors has completed enrollment with results posted…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations [Phase 1]
Phase 1 study of KIN-3248 in FGFR2/3-altered advanced tumors was terminated. The trial enrolled patients with intrahepatic cholangiocarcinom…
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CLINICAL_TRIALS trial_result · 2025-05-04Clinical Trial Update: Neoadjuvant and Adjuvant Durvalumab in Combination With Neoadjuvant Chemotherapy in Patients With Operable Urothelial Cancer. [Phase 2]
Phase 2 trial of durvalumab in combination with neoadjuvant chemotherapy for operable urothelial cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study to Evaluate the Clinical Efficacy of JNJ-42756493 (Erdafitinib), A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Participants With Advanced Non-Small-Cell Lung Cancer, Urothelial Cancer, Esophageal Cancer Or Cholangiocarcinoma [Phase 2]
A Phase 2 study completed in Asian participants evaluated Erdafitinib, a pan-FGFR tyrosine kinase inhibitor, for efficacy in advanced non-sm…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Study of Atezolizumab Combined With Split-dose Gemcitabine Plus Cisplatin in Urothelial Carcinoma [Phase 2]
Phase 2 study evaluating atezolizumab with split-dose gemcitabine plus cisplatin for locally advanced or metastatic urothelial carcinoma has…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Brazilian Reality of Urinary Bladder Cancers - BRA-BLADDER
AstraZeneca-sponsored BRA-BLADDER study evaluating bladder cancer in Brazil has completed, examining urothelial carcinoma across non-muscle …
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Phase 1b/2 Study of Rogaratinib (BAY1163877) in Combination With Atezolizumab in Urothelial Carcinoma [Phase 1]
Phase 1b/2 study evaluating Rogaratinib in combination with Atezolizumab in urothelial carcinoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: A Study to Learn About the Study Medicine (Avelumab) in Japanese Patients With Urothelial Carcinoma That Has Spread
This clinical trial update reports results from a study of Avelumab in Japanese patients with advanced urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Empa PASS on Urinary Tract Malignancies
Completed post-authorization safety study (PASS) evaluating empagliflozin for urinary tract malignancies with results posted.
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors [Phase 2]
Phase 2 study evaluating the efficacy of tislelizumab and spartalizumab across multiple cancers with PD-1 high mRNA expression; the trial is…
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Neoadjuvant Pembrolizumab in Combination With Gemcitabine Therapy in Cis-eligible/Ineligible UC Subjects [Phase 1, Phase 2]
A completed Phase 1/2 neoadjuvant trial evaluating pembrolizumab in combination with gemcitabine for cis-eligible and cis-ineligible urothel…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas [Phase 1]
Phase 1 trial evaluating SL-279252, a PD-1-Fc-OX40L fusion protein, in adults with advanced solid tumors or lymphomas has been completed wit…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Study of INCB086550 in Select Solid Tumors [Phase 2]
A Phase 2 trial evaluating INCB086550 across select solid tumors, including non-small cell lung cancer and urothelial carcinoma, was termina…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: An Umbrella Study to Determine the Safety and Efficacy of Various Monotherapy or Combination Therapies in Neoadjuvant Urothelial Carcinoma [Phase 2]
An umbrella Phase 2 trial evaluating multiple monotherapy and combination therapies in neoadjuvant urothelial carcinoma was terminated, and …