Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC) [Phase 1, Phase 2]
This is a clinical trial update for MORPHEUS-UC, a Phase 1/2 study evaluating multiple immunotherapy-based treatments and combinations in ur…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating cryoablation in combination with pembrolizumab or avelumab for metastatic urothelial carcinoma; the study is comple…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations [Phase 1, Phase 2]
Early-phase clinical update on TYRA-300 showing safety signals and preliminary anti-tumor activity in locally advanced or metastatic urothel…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers [Phase 1, Phase 2]
A Phase 1/2 study of OC-001 in locally advanced or metastatic cancers has been terminated according to its clinical trials registry listing.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: 18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy [EARLY_Phase 1]
An early-phase trial update reports results for using 18F-fluciclovine PET/CT to stage muscle-invasive bladder cancer before radical cystect…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer [Phase 1, Phase 2]
Update on a Phase II study evaluating Atezolizumab with cisplatin and gemcitabine as neoadjuvant therapy for bladder cancer; the trial is cu…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Neoadjuvant Toripalimab in Combination With Gemcitabine Therapy in Cisplatin Ineligible Local Advanved Bladder Cancer [Phase 2]
Phase 2 neoadjuvant trial of toripalimab in combination with gemcitabine for cisplatin-ineligible locally advanced urothelial carcinoma/blad…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Futibatinib and Pembrolizumab Combination in the Treatment of Advanced or Metastatic Urothelial Carcinoma [Phase 2]
Phase 2 study evaluating the combination of futibatinib and pembrolizumab for advanced or metastatic urothelial carcinoma was terminated, wi…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Zanzalintinib for Advanced Urothelial Carcinoma Progressing After Prior Therapy [Phase 2]
Phase 2 trial of zanzalintinib for advanced urothelial carcinoma progressing after prior therapy is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Combination of Avelumab and Taxane (AVETAX) for Urothelial Cancer [Phase 1]
This clinical trial update reports on a Phase 1 study evaluating the combination of avelumab with a taxane for urothelial carcinoma, which h…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: PROMOTE: Identifying Predictive Markers of Response for Genitourinary Cancer [NA]
PROMOTE is a UCSF-sponsored clinical trial aiming to identify predictive markers of response in genitourinary cancers, including prostate ca…
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE)
Clinical trial INSITE investigates pre-surgical identification of muscle-invasive tumor involvement in patients with urothelial carcinoma sc…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of INCB099318 in participants with advanced solid tumors has been terminated. The update reports safety, tolerability…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors [Phase 2]
This document provides an update on the Phase 2 trial of pemigatinib in non-muscle invasive bladder cancer patients with recurrent low- or i…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors [Phase 1]
Pfizer's PF-07820435 study in advanced solid tumors, including non-small-cell lung cancer and other indications, has been terminated at Phas…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors [Phase 1]
Phase 1a/1b study of TPST-1495 as monotherapy and in combination with pembrolizumab has completed status, spanning multiple solid tumors inc…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Trilaciclib, a CDK 4/6 Inhibitor, in Patients With Advanced/Metastatic Bladder Cancer Receiving Chemotherapy Then Avelumab [Phase 2]
This is a Phase 2 trial evaluating trilaciclib in combination with chemotherapy followed by avelumab for advanced/metastatic urothelial carc…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: A Study of ADRX-0706 in Select Advanced Solid Tumors [Phase 1]
Phase 1 study of ADRX-0706 in select advanced solid tumors is active/not recruiting, evaluating the investigational agent in triple-negative…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Immunotherapy With or Without Radiation Therapy for Metastatic Urothelial Cancer [Phase 2]
A Phase 2 trial of immunotherapy with or without radiation therapy for metastatic urothelial carcinoma, including platinum-resistant disease…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies [Phase 1]
Phase 1 dose-escalation and expansion study of intratumoral mRNA-2752 in advanced malignancies has completed, with expansion cohorts in seve…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Safety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory Cancer [Phase 1]
Phase 1 safety study evaluating enoblituzumab (MGA271) in combination with pembrolizumab or MGA012 in patients with refractory cancers. Resu…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Study to Evaluate Adverse Events and Change in Disease Activity When Intravenously (IV) Infused Livmoniplimab is Used in Combination With IV Infused Budigalimab in Adult Participants With Urothelial Carcinoma (UC) [Phase 2]
Phase 2 clinical trial evaluating adverse events and change in disease activity when livmoniplimab is used in combination with budigalimab i…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors [Phase 1]
Phase 1, first-in-human dose-finding and expansion study of XmAb808 in combination with pembrolizumab in advanced solid tumors; the trial ha…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: A Study of Evorpacept (ALX148) With Enfortumab Vedotin for Subjects With Urothelial Carcinoma (ASPEN-07) [Phase 1]
Phase 1 study ASPEN-07 evaluating Evorpacept (ALX148) with Enfortumab Vedotin for urothelial carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: HER2 and LA/mUC: A Multi-country Chart Review Cohort Study
A multi-country chart review cohort study evaluating HER2-directed therapy in locally advanced or metastatic urothelial carcinoma has comple…