Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program [Phase 2]
Phase 2 trial evaluating in-home versus in-clinic subcutaneous nivolumab administration under the CC Beyond Walls program; the study is curr…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma [Phase 2]
Phase 2 clinical trial evaluating consolidative local therapy for oligometastatic urothelial carcinoma, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC [Phase 1]
Phase 1 clinical trial evaluating intravesical adoptive cell therapy using tumor-infiltrating lymphocytes (TIL) for BCG-exposed high-grade n…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer. [Phase 1]
Phase 1 trial update of Naptumomab Estafenatox in combination with durvalumab in selected advanced or metastatic solid tumors, including eso…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC [Phase 1]
Phase 1 trial evaluating LB-LR1109 alone and in combination with atezolizumab for solid tumors, including non-small cell lung cancer, curren…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?
A recruiting clinical trial in women with isolated acute cystitis and macroscopic hematuria to evaluate the need for further investigation o…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Neoadjuvant Immune Checkpoint Inhibitor Treatment in Urothelial Cancer [Phase 2]
This clinical trial update describes a Phase 2 neoadjuvant treatment using an immune checkpoint inhibitor for urothelial carcinoma. Recruitm…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study) [NA]
A clinical trial is recruiting to evaluate a urine tumor DNA panel for screening urothelial cancer in individuals with Lynch syndrome (LS-UR…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression [Phase 1, Phase 2]
Clinical trial update for BT5528-100 (Phase 1/2) in EphA2-expressing advanced solid tumors. The study includes urothelial carcinoma, ovarian…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Ixazomib Citrate With Gemcitabine Hydrochloride and Doxorubicin Hydrochloride in Treating Patients With Urothelial Cancer That is Metastatic or Cannot Be Removed by Surgery [Phase 1, Phase 2]
A Phase 1/2 trial evaluating ixazomib citrate with gemcitabine and doxorubicin for metastatic or unresectable urothelial carcinoma; the stud…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Sacituzumab Govitecan Plus EV in Metastatic UC [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating sacituzumab govitecan in combination with Enfortumab Vedotin for metastatic urothelial cancer; the …
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial update describing safety, tolerability, and imaging with [68Ga]Ga-DPI-4452 and safety, tolerability, and efficacy…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer
A prospective validation trial evaluating high-volume urine DNA testing in individuals with suspected urothelial carcinoma.
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Neoadjuvant PD-1 Plus TIGIT Blockade in Patients With Cisplatin-Ineligible Operable High-Risk Urothelial Carcinoma [Phase 1, Phase 2]
A Phase 1/2 neoadjuvant trial is evaluating PD-1 blockade plus TIGIT blockade in cisplatin-ineligible operable high-risk urothelial carcinom…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Locally Advanced or Metastatic Urinary System Tumors [Phase 2]
Phase 2 clinical trial update for BL-B01D1 in patients with multiple solid tumors, including locally advanced or metastatic urinary system t…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma and Other Solid Tumors [Phase 2]
A Phase 2 study evaluating SI-B003 alone and in combination with BL-B01D1 in patients with locally advanced or metastatic urothelial carcino…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: TALazoparib and Avelumab as Maintenance Therapy in Platinum-Sensitive Metastatic or Locally Advanced URothelial Carcinoma [Phase 2]
Phase 2 trial evaluating talazoparib in combination with avelumab as maintenance therapy for platinum-sensitive urothelial carcinoma is curr…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Registry Platform Urologic Cancer
An ongoing clinical trial update from iOMEDICO AG describing a recruiting study for renal cell carcinoma and urothelial carcinoma.
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and Radiotherapy
A clinical trial is evaluating the combination of PD-1/PD-L1 immune checkpoint inhibitors with radiotherapy across several cancers to assess…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Compression Stockings to Prevent Peripheral Neuropathy Caused by Antibody-Drug Conjugates in Urothelial Carcinoma Patients [NA]
A clinical trial update describes evaluating compression stockings to prevent chemotherapy-induced peripheral neuropathy caused by antibody-…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Study of Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating pembrolizumab plus enfortumab vedotin, with or without investigational age…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Exploring Relevant Immune-based Biomarkers and Circulating Tumor Cells During Treatment With Immunotherapy in Genitourinary Malignancies (CTC Immune Based Biomarkers)
This clinical trial update describes a Duke University study evaluating immune-based biomarkers and circulating tumor cells in patients trea…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update evaluating the safety and efficacy of FF-10832 in combination with pembrolizumab for advanced urothelial carci…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab [Phase 2]
Phase 2 clinical trial update on Stage II-IIIa urothelial carcinoma evaluating pre-operative nivolumab with or without relatlimab. Recruitme…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Ivonescimab in the Treatment of Multiple Advanced Tumors [Phase 2]
An update indicating Ivonescimab is being studied in a Phase 2 trial for multiple advanced tumors and is currently recruiting. The trial cov…