Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer [Phase 3]
Phase 3 study evaluating durvalumab with chemotherapy, durvalumab plus tremelimumab with chemotherapy, or chemotherapy alone in patients wit…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: A Study to Evaluate Safety, Pharmacokinetics, & Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors; Urothelial Carcinoma Substudy in Association With RO7496353 Study GO44010 [Phase 1]
Phase 1 study GO44010 evaluates RO7496353 in combination with a checkpoint inhibitor (with or without standard chemotherapy) in locally adva…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Circulating Tumor DNA Response In Urothelial Cancer [Phase 2]
A Phase 2 clinical trial updating on circulating tumor DNA response in urothelial carcinoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Memory-like Natural Killer (NK) Cell Therapy in Patients With Renal Cell Carcinoma or Urothelial Carcinoma [EARLY_Phase 1]
This early-phase trial is evaluating memory-like natural killer (NK) cell therapy in patients with renal cell carcinoma and urothelial carci…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: SYS6002 vs PADCEV in Patients With Advanced Urothelial Carcinoma [Phase 2]
A Phase 2 trial is planned to compare SYS6002 with PADCEV (enfortumab vedotin) in adults with advanced urothelial carcinoma; the study is no…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Association Between the SPHERTEST in Vitro Test and Response to Checkpoint Inhibitor Treatments in Patients With Advanced or Metastatic Urothelial Carcinoma
This clinical trial explores whether SPHERTEST in vitro results correlate with responses to checkpoint inhibitor therapy in patients with ad…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy [NA]
This is an update on a clinical research study (NCT04623502) investigating kidney and urothelial tumor metabolism in patients undergoing sur…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Tremelimumab + Durvalumab(MEDI4736)+ Belinostat in Urothelial Carcinoma [Phase 1]
A Phase 1 trial evaluating a triple combination of tremelimumab, durvalumab, and belinostat in urothelial carcinoma; the study is currently …
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Cabozantinib in Combination With Enfortumab Vedotin for Locally Advanced or Metastatic Urothelial Cancer [Phase 1]
The document reports an ongoing Phase 1 trial evaluating cabozantinib in combination with Enfortumab Vedotin for locally advanced or metasta…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer [Phase 3]
This document reports on an ongoing Phase 3, single-arm study evaluating UGN-104 for low-grade upper urinary tract urothelial carcinoma, wit…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Criteria for Selecting First-line Metastatic Treatment for Patients With Urothelial Carcinoma
This clinical trial outlines criteria for selecting first-line metastatic treatment in patients with urothelial carcinoma and is currently r…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors [Phase 2]
ClinicalTrials.gov update for QUILT-3.055, a Phase 2 study of combination immunotherapies in patients who previously received immune checkpo…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial update for DECOY20 with or without tislelizumab in adults with advanced solid tumors across Phase 1 and Phase 2. The listed i…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Olfactive Detection of Urothelial Carcinoma by Sniffer Dogs
An ongoing clinical trial in Strasbourg is recruiting to evaluate whether trained sniffer dogs can detect urothelial carcinoma (bladder canc…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Pemetrexed and Avelumab in Treating Patients With MTAP-Deficient Metastatic Urothelial Cancer [Phase 2]
Phase 2 clinical trial evaluating pemetrexed in combination with avelumab for MTAP-deficient metastatic urothelial carcinoma; currently acti…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice
This clinical trial update reports on real-world outcomes and safety of atezolizumab in routine practice. It includes patients with urotheli…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Renal Retention in High Grade Upper Tract Urothelial Cancer [Phase 2]
A Phase 2 clinical trial at Johns Hopkins is recruiting to evaluate treatment for high-grade upper tract urothelial carcinoma and bladder ca…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: 9MW2821 Combined With Toripalimab in Perioperative Patients With Urothelial Cancer [Phase 2]
Phase 2 clinical trial of 9MW2821 in combination with toripalimab for perioperative urothelial carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Adjuvant Radioimmunotherapy Compared With Adjuvant Chemotherapy for UTUC
Recruitment is ongoing for a study comparing adjuvant radioimmunotherapy versus adjuvant chemotherapy in patients with upper tract urothelia…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Identification of Novel High Quality Methylated DNA Markers in Renal Tumors: Whole Methylome Discovery, Tissue Validation, and Feasibility Testing In Blood and Urine, The INQUIRE Study
A Mayo Clinic-led INQUIRE study is identifying novel high-quality methylated DNA markers for renal tumors. The project uses whole-methylome …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) [Phase 2]
Phase II trial evaluating trastuzumab deruxtecan (Trastuzumab Rezetecan) alone or in combination with Adebrelimab for HER2-expressing locall…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of INBRX-106 in combination with pembrolizumab for locally advanced or metastatic sol…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Combination of Ipi/Nivo Plus Sacituzumab Govitecan in Metastatic Cisplatin Ineligible Urothelial Carcinoma Patients [Phase 1, Phase 2]
A Phase 1/2 trial is evaluating the combination of ipilimumab, nivolumab, and sacituzumab govitecan in metastatic cisplatin-ineligible uroth…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A Study to Compare the Results of FGFR Testing by Either ctDNA Blood Testing or Standard Tumor Tissue Testing
A clinical study comparing FGFR testing results obtained from ctDNA blood testing to standard tumor tissue testing in metastatic bladder can…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Evolution of Proteomic Profiles of Intestinal Microbiota in Patients With Locally Advanced or Metastatic Urothelial Carcinomas
This clinical trial update reports on the evolution of proteomic profiles of the intestinal microbiota in patients with locally advanced or …