Ulcerative Colitis
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: A Clinical Trial to Assess the Safety of SOR102 in Healthy Participants and Patients With Ulcerative Colitis [Phase 1]
Phase 1 clinical trial completed to assess the safety of SOR102 in healthy participants and patients with ulcerative colitis.
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: Comparison of PillCamCOLON (C2) Capsule and Standard Endoscopy for the Evaluation of Patients With Ulcerative Colitis [NA]
This clinical trial compared PillCamCOLON capsule endoscopy with standard endoscopy for evaluating patients with ulcerative colitis. The stu…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: A Phase 2a Open-Label Study to Evaluate the Efficacy and Safety of MORF-057 in Adults With UC [Phase 2]
This Phase 2a open-label study evaluated MORF-057 for efficacy and safety in adults with ulcerative colitis. The trial is completed and resu…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: High Dose Steroid Therapy to Treat Flares in Patients With Inflammatory Bowel Disease (IBD) [Phase 1]
Phase 1 trial evaluating high-dose systemic corticosteroid therapy to treat flares in inflammatory bowel disease has completed.
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Combination Therapy With Fecal Microbiota Transplantation and Vedolizumab for Induction of Ulcerative Colitis [Phase 4]
Phase 4 trial evaluating induction of ulcerative colitis with a combination of fecal microbiota transplantation and vedolizumab has been com…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Investigating the Anti-inflammatory Effects of Frondanol in Adults With Inflammatory Bowel Disease [Phase 2, Phase 3]
The study update indicates completion of Phase 2 and Phase 3 trials evaluating Frondanol for anti-inflammatory effects in adults with inflam…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial update reports results for guselkumab in adults with moderately to severely active ulcerative colitis, spon…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis [Phase 2, Phase 3]
A study evaluating guselkumab in moderately to severely active ulcerative colitis across Phase 2 and Phase 3 is ongoing with results posted …
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CLINICAL_TRIALS trial_result · 2024-11-13Clinical Trial Update: VTX002 Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis [Phase 2]
Phase 2 trial of VTX002 versus placebo for moderately to severely active ulcerative colitis has results posted; trial is currently active bu…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: A Study of Moderate to Severe Inflammatory Bowel Disease, Including Ulcerative Colitis (UC) and Crohn's Disease (CD)
Takeda-sponsored trial evaluating a treatment for moderate-to-severe inflammatory bowel disease, including ulcerative colitis and Crohn's di…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Entyvio (Vedolizumab) Long Term Safety Study
This document reports the completion of a long-term safety study of Vedolizumab (Entyvio) in ulcerative colitis and Crohn's disease.
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Evaluation of the Effectiveness of Kits Promonitor-IFX/ADL and Promonitor-Anti-IFX/ADL in Patients With IBD
This clinical trial update reports on the effectiveness of Promonitor-IFX/ADL and Promonitor-Anti-IFX/ADL kits in patients with inflammatory…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Etrasimod Dose-Ranging Versus Placebo as Induction Therapy Study in Adult Japanese Subjects With Moderately to Severely Active Ulcerative Colitis [Phase 2]
Pfizer conducted a Phase 2 dose-ranging trial of etrasimod versus placebo as induction therapy in adult Japanese patients with moderately to…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Comparison Between Infliximab and Adalimumab on Patients With Ulcerative Colitis
A completed clinical trial comparing the efficacy and safety of infliximab versus adalimumab in patients with ulcerative colitis.
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Study for Participants With Ulcerative Colitis Previously Enrolled in Etrolizumab Phase II/III Studies [Phase 3]
A Phase III study of etrolizumab in ulcerative colitis has been terminated; results were posted after termination.
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in Real-World Practice
This update reports the completion of a real-world study evaluating vedolizumab in adults with ulcerative colitis or Crohn's disease.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Xeljanz Special Investigation for Long-term Use in UC Patients
Pfizer's Xeljanz (tofacitinib) long-term-use study in ulcerative colitis has completed and results were posted on 2024-10-08.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Optimising Infliximab Induction Therapy for Acute Severe Ulcerative Colitis [Phase 4]
Phase 4 trial investigating optimized induction regimens of infliximab for adults with acute severe ulcerative colitis has completed.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: OTIS Vedolizumab Pregnancy Exposure Registry
This clinical trial registry update reports that the OTIS Vedolizumab Pregnancy Exposure Registry (NCT02678052) has completed data collectio…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: A Study Evaluating the Effect of Filgotinib Dose De-escalation in Participants With Ulcerative Colitis (UC) in Remission [Phase 3]
Phase 3 study evaluating dose de-escalation of filgotinib in ulcerative colitis patients in remission was terminated, with results posted on…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: COlonic Salvage by Therapeutic Appendectomy. [NA]
A clinical trial evaluating colonic salvage using therapeutic appendectomy in ulcerative colitis has completed.
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Transcutaneous VNS to Treat Pediatric IBD [NA]
A completed clinical trial evaluating transcutaneous vagus nerve stimulation for pediatric inflammatory bowel disease. The study included ch…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: A Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Crohn's Disease or Ulcerative Colitis [Phase 2]
Phase 2 trial update evaluating the long-term safety and efficacy of deucravacitinib in participants with Crohn's disease or ulcerative coli…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Erythrocytes-Mediated Delivery Of Dexamethasone 21-Phosphate In Steroid-Dependent Ulcerative Colitis [Phase 2]
Phase 2 study evaluating erythrocyte-mediated delivery of dexamethasone 21-phosphate for steroid-dependent ulcerative colitis has completed …
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: This Study is to Describe and Evaluate Patients in Finland Treated With Tofacitinib for the Treatment of Ulcerative Colitis Using Real World Data.
This clinical trial update describes a completed real-world study in Finland evaluating the use of tofacitinib for ulcerative colitis and no…