Ulcerative Colitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis [Phase 3]
A Phase 3 induction trial is evaluating the efficacy and safety of Duvakitug in participants with moderately to severely active ulcerative c…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Upadacitinib Versus Infliximab as Second-Line Treatment for Acute Severe Ulcerative Colitis（UPRISE） [Phase 4]
Phase 4 trial comparing upadacitinib to infliximab as second-line therapy for acute severe ulcerative colitis is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)
This clinical trial update notes ongoing Seattle Children's Hospital research evaluating spatial transcriptomics in inflammatory bowel disea…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Implementing a Multimodal RCT Intervention to Improve the Transition of Patients With Crohn's Disease From Pediatric to Adult Care [NA]
This clinical trial update describes a multimodal randomized controlled trial to improve the transition of patients with Crohn's disease fro…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Association Between LRG and Histologic Remission in Ulcerative Colitis
This clinical trial investigates the association between LRG levels and histologic remission in ulcerative colitis and is currently recruiti…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Predictors of Prognosis in IBD Patients
A clinical trial is investigating predictors of prognosis in patients with inflammatory bowel diseases, including ulcerative colitis and Cro…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis [Phase 3]
A Phase 3 clinical trial is evaluating Afimkibart (RO7790121) in children with moderately to severely active ulcerative colitis, with recrui…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of SAR442970 in adult participants with ulcerative colitis; recruiting.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: AI-Enhanced Wide-Field Endoscopic Fluorescence Mapping of Gastrointestinal Mucosal Permeability in IBD - A Pilot Study in IBD Patients and Controls
This pilot clinical trial examines AI-enhanced wide-field endoscopic fluorescence mapping to evaluate gastrointestinal mucosal permeability …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: The Effect of VSL#3 Probiotic Preparation on the Bile Acid Metabolism in Patients With Inflammatory Bowel Disease [NA]
A clinical trial is evaluating the effect of the probiotic preparation VSL#3 on bile acid metabolism in patients with inflammatory bowel dis…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Multi-omics Dissection of Gut Microbiome Engraftment During FMT [NA]
Clinical trial update for a NOT_YET_RECRUITING study examining gut microbiome engraftment during fecal microbiota transplantation in recurre…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: BCMA-CD19 cCAR T for the Treatment of Refractory Inflammatory Bowel Disease (IBD) [Phase 1, Phase 2]
A Phase 1/2 clinical trial update describes BCMA-CD19 cCAR T therapy for refractory inflammatory bowel disease, with trial status NOT_YET_RE…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting [Phase 4]
Phase 4 clinical trial update for Vedolizumab in adults with Ulcerative colitis or Crohn's disease in the community setting; the study is cu…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis [Phase 2]
A Phase 2 clinical trial is evaluating LY4268989 in adults with moderately to severely active ulcerative colitis and is currently recruiting…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Comparative Effectiveness of Upadacitinib vs Corticosteroids as First-Line Therapy for Acute Severe Ulcerative Colitis（UPFRONT） [Phase 4]
A Phase 4 clinical trial is evaluating the comparative effectiveness of upadacitinib versus corticosteroids as initial therapy for acute sev…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002) [Phase 2]
Phase 2 clinical trial MK-8690-002 evaluating efficacy and safety of MK-8690 in moderately to severely active ulcerative colitis is currentl…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO [Phase 1]
Phase 1 trial evaluating nivolumab in patients with autoimmune disorders and advanced cancers; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Real-World Study of Guselkumab in Ulcerative Colitis and Crohn's Disease in Saudi Arabia
This is a real-world clinical trial in Saudi Arabia evaluating guselkumab for ulcerative colitis and Crohn's disease, with status not yet re…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis
An observational prospective long-term exposure registry sponsored by Janssen Biotech to monitor safety and real-world use in adults with mo…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis [Phase 2]
Phase 2 study evaluating Eltrekibart and Mirikizumab in adults with moderately to severely active Ulcerative Colitis; the trial is currently…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Confirmatory Clinical Study in Active Ulcerative Colitis [Phase 2]
Phase 2 confirmatory clinical study in active ulcerative colitis is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis: [Phase 2]
A Phase 2 clinical trial evaluating LY4268989 (MORF-057) in combination with mirikizumab for adults with moderately to severely active ulcer…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)
The COMPARE trial for pediatric inflammatory bowel disease is currently recruiting, evaluating treatments for pediatric ulcerative colitis a…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate to Severe Active Ulcerative Colitis [Phase 1, Phase 2]
Genentech is conducting a Phase 1/2 clinical trial to evaluate the activity and safety of Vixarelimab in participants with moderate to sever…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study [Phase 3]
A Phase 3b trial is evaluating concurrent administration of mirikizumab with tirzepatide in adults with moderately to severely active ulcera…