Type 2 Diabetes Mellitus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2010-10-19Clinical Trial Update: A Drug Interaction Study Between Simvastatin and GSK376501 [Phase 1]
A Phase 1 study assessed the potential interaction between simvastatin and the investigational GSK376501; the trial in Type 2 Diabetes Melli…
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CLINICAL_TRIALS trial_result · 2010-10-18Clinical Trial Update: MK0431A vs. Pioglitazone in Patients With Type 2 Diabetes Mellitus (0431A-066) [Phase 3]
Phase 3 trial comparing MK0431A to pioglitazone in adults with Type 2 diabetes mellitus has completed. Results were posted in October 2010.
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CLINICAL_TRIALS trial_result · 2010-10-15Clinical Trial Update: Study To Investigate The Safety And Metabolism Of GSK376501 In Overweight Subjects [Phase 1]
The update describes the completion of a Phase 1 study evaluating the safety and metabolism of GSK376501 in overweight adults with Type 2 di…
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CLINICAL_TRIALS trial_result · 2010-10-14Clinical Trial Update: Bioequivalence Study of Metformin Hydrochloride Extended Release 750 mg Tablets Versus Glucophage XR® 750 mg Tablet in Healthy Volunteers Under Fasting Conditions. [Phase 1]
Phase 1 bioequivalence study comparing metformin hydrochloride extended-release 750 mg tablets to Glucophage XR 750 mg in healthy volunteers…
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CLINICAL_TRIALS trial_result · 2010-10-13Clinical Trial Update: Effects of Insulin in Perceived Mood Symptoms in Patients With Type 2 Diabetes [Phase 4]
A Phase 4 clinical trial evaluating the effects of insulin on perceived mood symptoms in adults with type 2 diabetes; the study sponsored by…
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CLINICAL_TRIALS trial_result · 2010-10-13Clinical Trial Update: Efficacy and Safety of Twice-Daily Insulin Lispro Low Mixture Compared to a Once-Daily Long Acting Insulin Comparator in Patients Who Have Been Using One or More Oral Antihyperglycemic Agents Without Insulin [Phase 4]
Phase 4 clinical trial comparing twice-daily insulin lispro low mixture with a once-daily long-acting insulin in type 2 diabetes patients pr…
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CLINICAL_TRIALS trial_result · 2010-10-13Clinical Trial Update: 24 Hour Plasma Glucose Profiles Comparing Lispro Mix 75/25 vs. Glargine [Phase 4]
This Phase 4 trial compared 24-hour plasma glucose profiles between insulin lispro mix 75/25 and insulin glargine in adults with type 2 diab…
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CLINICAL_TRIALS trial_result · 2010-10-13Clinical Trial Update: Long-Term Effects of Insulin Plus Metformin Regimens on the Overall and Postprandial Glycemic Control of Patients With Type 2 Diabetes [Phase 4]
A Phase 4 clinical trial update from Eli Lilly evaluated long-term effects of insulin plus metformin on overall and postprandial glycemic co…
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CLINICAL_TRIALS trial_result · 2010-10-11Clinical Trial Update: Secondary Prevention in Type 2 Diabetes: Comparison of Two Different Resistance Exercise Training Protocols [Phase 1]
This clinical trial update reports on a Phase 1 study comparing two resistance exercise training protocols for secondary prevention in Type …
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CLINICAL_TRIALS trial_result · 2010-10-11Clinical Trial Update: The Effect of Sitagliptin in Type 2 Diabetes Mellitus With Inadequate Glycemic Control (MK0431-118) [Phase 4]
Phase 4 trial evaluating sitagliptin in adults with type 2 diabetes and inadequate glycemic control was terminated; results were posted in 2…
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CLINICAL_TRIALS trial_result · 2010-10-08Clinical Trial Update: Orthostatic Hypotension and Diabetes Mellitus
A completed clinical trial sponsored by the Medical Research Foundation in the Netherlands investigated orthostatic hypotension and type 2 d…
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CLINICAL_TRIALS research · 2010-10-08Clinical Trial Update: Diabetes IN-CHARGE: Trial of Diabetes Intervention in the Community to Help Achieve Reduced Glucose Elevation [NA]
Diabetes IN-CHARGE is a McMaster University–sponsored clinical trial evaluating a community-based intervention to reduce glucose elevation i…
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CLINICAL_TRIALS trial_result · 2010-10-07Clinical Trial Update: Insulin Glargine at Bedtime or in AM Versus NPH [Phase 4]
A Phase 4 trial comparing bedtime or morning administration of insulin glargine versus NPH insulin in adults with Type 2 Diabetes Mellitus h…
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CLINICAL_TRIALS trial_result · 2010-10-07Clinical Trial Update: Insulin Glargine Versus Twice-Daily NPH [Phase 4]
Phase 4 trial comparing insulin glargine to twice-daily NPH in type 2 diabetes was terminated, with results posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-10-06Clinical Trial Update: Efficacy of Pioglitazone/Metformin Combination Therapy in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia. [Phase 3]
Phase 3 trial evaluating the efficacy of a pioglitazone/metformin combination in adults with type 2 diabetes mellitus and dyslipidemia; resu…
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CLINICAL_TRIALS research · 2010-10-06Clinical Trial Update: A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents
A retrospective cohort study evaluating the relationship between exenatide (and other antidiabetic therapies) and acute pancreatitis, with r…
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CLINICAL_TRIALS trial_result · 2010-10-05Clinical Trial Update: A Study to Test the Safety and Efficacy of Sitagliptin Compared to Glimepiride in Patients With Type 2 Diabetes on a Stable Dose of Metformin (0431-803)(COMPLETED) [Phase 3]
A Phase 3 randomized trial comparing sitagliptin to glimepiride as add-on therapy to metformin in adults with type 2 diabetes has completed …
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CLINICAL_TRIALS research · 2010-10-05Clinical Trial Update: A Two Part Study of Peroral Insulin in Type 2 Diabetes [Phase 1, Phase 2]
A two-part Phase 1/2 trial of an orally administered insulin for Type 2 diabetes has been suspended.
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CLINICAL_TRIALS trial_result · 2010-09-30Clinical Trial Update: 1,5-AG as a Marker of Postprandial Hyperglycemia and Glucose Variability in Well-controlled Type 2 Diabetes Mellitus
This clinical trial evaluated 1,5-anhydroglucitol (1,5-AG) as a biomarker of postprandial hyperglycemia and glucose variability in well-cont…
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CLINICAL_TRIALS trial_result · 2010-09-28Clinical Trial Update: Efficacy of DLBS-32 in Subjects With Type-II Diabetes Mellitus [Phase 2]
Phase 2 clinical trial evaluating the efficacy of DLBS-32 for type 2 diabetes mellitus has completed.
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FDA approval · 2010-09-24FDA Approved: JANUMET — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approved a supplemental application for JANUMET (sitagliptin and metformin hydrochloride) from Merck Sharp & Dohme LLC.
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CLINICAL_TRIALS trial_result · 2010-09-24Clinical Trial Update: Effect of Alpha Lipoic Acid on Obesity Related Comorbidities [Phase 2, Phase 3]
Clinical trial update reporting results from a Phase 2/Phase 3 study of alpha lipoic acid on obesity-related comorbidities, completed status…
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EMA safety_alert · 2010-09-23European Medicines Agency recommends suspension of Avandia, Avandamet and Avaglim
The EMA recommends suspension of the diabetes medicines rosiglitazone-containing products Avandia, Avandamet, and Avaglim due to cardiovascu…
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FDA approval · 2010-09-23FDA Approved: GLYBURIDE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for glyburide from Teva Pharmaceuticals USA, Inc. The approval indicates changes to an already appro…
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FDA approval · 2010-09-23FDA Approved: PIOGLITAZONE AND GLIMEPIRIDE — Supplemental Application (Prasco Laboratories)
The FDA approval of a supplemental application for Pioglitazone and Glimepiride submitted by Prasco Laboratories. This action pertains to a …