Type 2 Diabetes Mellitus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-02-22Clinical Trial Update: Study To Evaluate The Effect Of Renal Impairment On The Pharmacokinetics Of PF-04991532 [Phase 1]
A Phase 1 study completed to evaluate how renal impairment affects the pharmacokinetics of PF-04991532 in individuals with Type 2 diabetes m…
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CLINICAL_TRIALS withdrawal · 2012-02-22Clinical Trial Update: Telephone Intervention in Patients With Acute Coronary Syndrome (ACS) and Diabetes [NA]
A clinical trial evaluating a telephone intervention for patients with acute coronary syndrome and type 2 diabetes was terminated.
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CLINICAL_TRIALS trial_result · 2012-02-20Clinical Trial Update: Efficacy and Safety of BI 1356 in Combination With Metformin in Patients With Type 2 Diabetes [Phase 3]
A Phase 3 study evaluated the efficacy and safety of BI 1356 in combination with metformin in patients with Type 2 diabetes. Results were po…
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CLINICAL_TRIALS trial_result · 2012-02-20Clinical Trial Update: Dose Finding, Safety and Efficacy of Monthly Subcutaneous Canakinumab Administration in Metformin Monotherapy Treated Type 2 Diabetic Patients [Phase 2, Phase 3]
A Phase 2/3 trial evaluating monthly subcutaneous canakinumab in metformin-treated type 2 diabetes patients was terminated, with results pos…
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CLINICAL_TRIALS trial_result · 2012-02-17Clinical Trial Update: A Study to Test the Effectiveness and Safety of MK0893 in Combination With Other Drugs Used to Treat Type 2 Diabetes (0893-015) [Phase 2]
A Phase 2 trial evaluated the effectiveness and safety of MK0893 in combination with other antidiabetic drugs for type 2 diabetes; the study…
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CLINICAL_TRIALS trial_result · 2012-02-17Clinical Trial Update: Stem Cell Educator Therapy in Type 2 Diabetes [Phase 1, Phase 2]
The clinical trial update reports the completion of Phase 1/2 testing of Stem Cell Educator Therapy for Type 2 diabetes mellitus conducted b…
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CLINICAL_TRIALS trial_result · 2012-02-13Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 in Patients With Type 2 Diabetes [Phase 2]
Phase 2 trial update reporting safety, tolerability, and pharmacokinetics/pharmacodynamics of ACZ885 (canakinumab) in patients with Type 2 D…
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CLINICAL_TRIALS trial_result · 2012-02-13Clinical Trial Update: Safety, Tolerability and Pharmacodynamics of CYT013-IL1bQb in Patients With Type 2 Diabetes [Phase 1]
A Phase 1 study assessing safety, tolerability and pharmacodynamics of CYT013-IL1bQb in patients with Type 2 Diabetes.
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CLINICAL_TRIALS trial_result · 2012-02-13Clinical Trial Update: Japanese Single and Multiple Ascending Dose, Safety, Tolerability, Pharmacokinetic (PK) & Pharmacodynamic (PD) Study of AZD7687 [Phase 1]
This is a Phase 1 Japanese single and multiple ascending dose study of AZD7687 assessing safety, tolerability, pharmacokinetics and pharmaco…
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CLINICAL_TRIALS trial_result · 2012-02-13Clinical Trial Update: Polyphenols and Insulin Resistance [NA]
This entry notes a completed clinical trial evaluating polyphenols for insulin resistance, conducted in healthy volunteers and individuals w…
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FDA approval · 2012-02-09FDA Approved: METFORMIN HYDROCHLORIDE — Supplemental Application (Mylan Pharmaceuticals Inc.)
The FDA approved a supplemental application for METFORMIN HYDROCHLORIDE submitted by Mylan Pharmaceuticals Inc., authorizing an approved mod…
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CLINICAL_TRIALS trial_result · 2012-02-09Clinical Trial Update: Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes Splicing [NA]
A completed clinical trial evaluating metformin's effect on alternative gene splicing in patients with type 2 diabetes.
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CLINICAL_TRIALS trial_result · 2012-02-08Clinical Trial Update: Bioequivalence Study of Fixed Dose Combination of 2.5 mg Saxagliptin/850 mg Metformin Tablet Relative to 2.5 mg Onglyza and 850 mg Glucophage Tablets Co-Administered [Phase 1]
A Phase 1 bioequivalence study comparing a fixed-dose combination tablet of saxagliptin 2.5 mg and metformin 850 mg with co-administered sax…
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FDA approval · 2012-02-07FDA Approved: ACARBOSE — Original Application (Chartwell RX, LLC)
The FDA approved Chartwell RX, LLC's original ANDA for acarbose, a generic medication used to help manage blood glucose in type 2 diabetes.
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CLINICAL_TRIALS research · 2012-02-07Clinical Trial Update: Roux-en-Y Versus Billroth II Reconstruction After Subtotal Gastrectomy in Gastric Cancer Comorbid With Type II Diabetes [Phase 2, Phase 3]
A phase 2/3 trial compares Roux-en-Y versus Billroth II reconstruction after subtotal gastrectomy in patients with gastric cancer and type 2…
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CLINICAL_TRIALS research · 2012-02-06Clinical Trial Update: The Verona Newly Diagnosed Type 2 Diabetes Study
This document provides an update on a Verona-based clinical trial for newly diagnosed Type 2 Diabetes Mellitus. The current trial status is …
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CLINICAL_TRIALS trial_result · 2012-02-03Clinical Trial Update: Safety, Tolerability and Activity Study of Multiple Doses of ISIS-SGLT2Rx in Healthy Volunteers [Phase 1]
Phase 1 safety and tolerability study of multiple doses of ISIS-SGLT2Rx in healthy volunteers, with exploratory activity assessments related…
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FDA approval · 2012-02-02FDA Approved: JANUMET XR — Original Application (Merck Sharp & Dohme LLC)
FDA approved JANUMET XR, a new extended-release formulation combining sitagliptin and metformin hydrochloride for type 2 diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2012-02-02Clinical Trial Update: Efficacy and Safety of TAK-559 Combined With Glyburide in Treating Subjects With Type 2 Diabetes Mellitus. [Phase 3]
Phase 3 trial evaluating TAK-559 plus glyburide in Type 2 diabetes mellitus was terminated; the update reports efficacy and safety data obse…
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CLINICAL_TRIALS trial_result · 2012-02-02Clinical Trial Update: Exploratory Study of Iocide Oral Rinse in a Diabetic Population [Phase 1]
An exploratory Phase 1 study evaluating Iocide Oral Rinse in adults with Type 2 diabetes mellitus and periodontitis has completed.
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CLINICAL_TRIALS trial_result · 2012-02-02Clinical Trial Update: To Assess Safety, Tolerability, Pharmacokinetics/Pharmacodynamics and the Effect of Fasting After Single Oral Doses of AZD5658 in Type 2 Diabetes [Phase 1]
It summarizes a completed Phase 1 trial assessing safety, tolerability, pharmacokinetics/pharmacodynamics, and the effect of fasting after a…
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CLINICAL_TRIALS trial_result · 2012-02-02Clinical Trial Update: Evaluation of the Tantalus System in Type 2 Diabetic Subjects [Phase 1]
This clinical trial update reports the completion of a Phase 1 evaluation of the Tantalus System in adults with Type 2 diabetes mellitus and…
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CLINICAL_TRIALS trial_result · 2012-02-01Clinical Trial Update: Safety and Efficacy in Type 2 Diabetic Patients With Severe Chronic Renal Impairment, 5 mg BI 1356 (Linagliptin) vs. Placebo, Insulin Background Inclusive [Phase 3]
Phase 3 trial evaluating safety and efficacy of linagliptin 5 mg vs placebo in adults with type 2 diabetes and severe chronic kidney impairm…
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CLINICAL_TRIALS trial_result · 2012-02-01Clinical Trial Update: Sitagliptin (MK-0431) vs. Placebo in Patients With Inadequate Glycemic Control on Metformin With Pioglitazone (MK-0431-128) [Phase 3]
A Phase 3 trial comparing sitagliptin to placebo in adults with type 2 diabetes and inadequate glycemic control on metformin with pioglitazo…
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CLINICAL_TRIALS trial_result · 2012-01-31Clinical Trial Update: Metformin Effects on Oxidative Stress Parameters in Newly Diagnosed Type 2 Diabetes Patients [NA]
This Clinical Trial Update reports on a study investigating the effects of metformin on oxidative stress parameters in newly diagnosed Type …