Type 2 Diabetes Mellitus
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CLINICAL_TRIALS trial_result · 2012-10-03Clinical Trial Update: Lifestyle Intervention in a General Population for Prevention of Ischaemic Heart Disease [NA]
A completed clinical trial evaluating a lifestyle intervention in the general population for the prevention of ischemic heart disease; the e…
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CLINICAL_TRIALS trial_result · 2012-10-02Clinical Trial Update: The Effect of A-lipoic Acid (ALA) on Fatty Acid-induced Impairment of Glucose-stimulated Insulin Secretion [Phase 4]
Phase 4 study evaluating the effect of alpha-lipoic acid on fatty acid-induced impairment of glucose-stimulated insulin secretion in people …
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CLINICAL_TRIALS trial_result · 2012-10-01Clinical Trial Update: Pharmacokinetic Profile of Two Formulations of PB1023 Following Single Subcutaneous Injection in Subjects With Type 2 Diabetes Mellitus [Phase 1]
Phase 1 trial update evaluating the pharmacokinetic profile of two PB1023 formulations after a single subcutaneous injection in adults with …
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CLINICAL_TRIALS trial_result · 2012-10-01Clinical Trial Update: Tissue Distribution of F18-FDG Labelled Autologous Bone Marrow Derived Stem Cells in Patients With Type 2 DM [Phase 2, Phase 3]
This clinical trial update reports on the tissue distribution of F18-FDG labeled autologous bone marrow–derived stem cells in patients with …
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FDA approval · 2012-09-28FDA Approved: COZAAR — Supplemental Application (Organon LLC)
FDA approved a supplemental application for Cozaar (losartan potassium) filed by Organon LLC.
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FDA approval · 2012-09-28FDA Approved: TRADJENTA — Supplemental Application (Boehringer Ingelheim Pharmaceuticals, Inc.)
The FDA approved a supplemental application for Tradjenta (linagliptin) submitted by Boehringer Ingelheim Pharmaceuticals, Inc. This action …
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FDA approval · 2012-09-27FDA Approved: GLYBURIDE — Supplemental Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
FDA approved a supplemental application for glyburide from Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. The action represen…
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CLINICAL_TRIALS trial_result · 2012-09-27Clinical Trial Update: Efficacy and Safety of Linagliptin in Combination With Insulin in Patients With Type 2 Diabetes [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of adding linagliptin to insulin therapy in patients with type 2 diabetes. Results have b…
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CLINICAL_TRIALS trial_result · 2012-09-27Clinical Trial Update: Anti-Inflammatory Effects of Pioglitazone [NA]
A completed clinical trial investigated the anti-inflammatory effects of pioglitazone in individuals with impaired glucose tolerance and typ…
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FDA approval · 2012-09-25FDA Approved: JENTADUETO — Supplemental Application (Boehringer Ingelheim Pharmaceuticals, Inc.)
FDA approved a supplemental application for JENTADUETO (linagliptin and metformin HCl) from Boehringer Ingelheim Pharmaceuticals, Inc., appr…
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CLINICAL_TRIALS trial_result · 2012-09-25Clinical Trial Update: Impact of Genetics on Metformin Pharmacokinetics [NA]
This clinical trial update notes a completed study from UCSF investigating how genetic variation affects metformin pharmacokinetics.
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CLINICAL_TRIALS research · 2012-09-24Clinical Trial Update: Virtual World Health Behavior Counseling for Patients With Diabetes [Phase 1, Phase 2]
Clinical trial evaluating virtual world health behavior counseling for patients with Type 2 diabetes mellitus, completed Phase 1 and Phase 2…
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FDA approval · 2012-09-19FDA Approved: METFORMIN HYDROCHLORIDE — Supplemental Application (Amneal Pharmaceuticals LLC)
FDA approved a Supplemental Application for Metformin Hydrochloride by Amneal Pharmaceuticals LLC. This constitutes a new generic drug appro…
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CLINICAL_TRIALS research · 2012-09-18Clinical Trial Update: The Metabolic Effects of Acute Hyperglycemia in Patients With Type 2 Diabetes [NA]
This clinical trial update reports on a completed study evaluating the metabolic effects of acute hyperglycemia in patients with type 2 diab…
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CLINICAL_TRIALS trial_result · 2012-09-18Clinical Trial Update: Endothelial and Metabolic Effects of Glucagon-like Peptide-1 (GLP-1) in Coronary Circulation in Patients With Type 2 Diabetes Mellitus [NA]
A completed clinical trial assessing the effects of glucagon-like peptide-1 on endothelial function and coronary circulation in patients wit…
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CLINICAL_TRIALS trial_result · 2012-09-13Clinical Trial Update: TAK-875 Glimepiride Drug-Interaction Study [Phase 1]
A Phase 1 pharmacokinetic study evaluating potential drug interaction between TAK-875 (fasiglifam) and glimepiride has completed.
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CLINICAL_TRIALS trial_result · 2012-09-13Clinical Trial Update: Normalization of Fasting Glucose and the Incidence of Restenosis After Peripheral Angioplasty [Phase 4]
Phase 4 clinical trial evaluating normalization of fasting glucose and the incidence of restenosis after peripheral angioplasty in patients …
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FDA approval · 2012-09-11FDA Approved: GLYBURIDE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
The FDA has approved a supplemental application for glyburide from Teva Pharmaceuticals USA, Inc., under an ANDA.
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CLINICAL_TRIALS trial_result · 2012-09-11Clinical Trial Update: Metabolic Activation With Almased for Type 2 Diabetes Patients [EARLY_Phase 1]
A completed early-phase clinical trial evaluating metabolic activation with Almased in adults with Type 2 Diabetes Mellitus.
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CLINICAL_TRIALS research · 2012-09-11Clinical Trial Update: A Cohort Study of Incretin-based Therapy Combined With Insulin in Type 2 Diabetic Patients for 5 Years [NA]
This document reports a 5-year cohort study evaluating incretin-based therapy combined with insulin in patients with Type 2 Diabetes Mellitu…
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CLINICAL_TRIALS trial_result · 2012-09-10Clinical Trial Update: Nutritional Intervention With Moderately High-protein, Low-glycemic Load Products in Type-2 Diabetes Patients [NA]
This clinical trial update notes a completed study evaluating moderately high-protein, low-glycemic-load nutritional products in adults with…
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CLINICAL_TRIALS trial_result · 2012-09-07Clinical Trial Update: A Study to Test the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK1006 (MK-1006-002)(COMPLETED) [Phase 1]
A completed Phase 1 trial evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of MK-1006 in individuals with type 2 …
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CLINICAL_TRIALS trial_result · 2012-09-06Clinical Trial Update: Study of VI-0521 Compared to Placebo in Treatment of Diabetes and Obesity in Adults With Obesity-Related Co-Morbid Conditions [Phase 3]
Phase 3 study VI-0521 versus placebo in adults with obesity and obesity-related comorbid conditions completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2012-09-05Clinical Trial Update: Study to Evaluate the Pharmacokinetics & Food Effect of MK-0941 in Adults With Type 2 Diabetes (MK-0941-009) [Phase 1]
A Phase 1 pharmacokinetics and food-effect study of MK-0941 in adults with Type 2 diabetes mellitus; the trial (NCT00567112) is completed an…
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CLINICAL_TRIALS research · 2012-09-05Clinical Trial Update: Mobile Health Technology as an Intervention for Diabetes Self-Management [NA]
This entry provides an update on a clinical trial examining mobile health technology to support self-management of Type 2 diabetes mellitus.