Type 2 Diabetes Mellitus
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CLINICAL_TRIALS trial_result · 2013-12-05Clinical Trial Update: Effects of a Mediterranean Style Diet on Vascular Health in Type 2 Diabetes [NA]
This document reports the completion of a clinical trial assessing the effects of a Mediterranean-style diet on vascular health in individua…
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CLINICAL_TRIALS trial_result · 2013-12-04Clinical Trial Update: The Contribution of Incretin Hormones to Post-prandial Glucose Metabolism After Roux-en-Y Gastric Bypass [EARLY_Phase 1]
An EARLY Phase 1 study investigates how incretin hormones influence post-prandial glucose metabolism after Roux-en-Y gastric bypass in peopl…
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CLINICAL_TRIALS trial_result · 2013-12-04Clinical Trial Update: The Contribution of Incretin Hormones to the Amelioration of Glucose Metabolism After Roux-en-Y Gastric Bypass [EARLY_Phase 1]
An early-phase 1 trial investigated the contribution of incretin hormones to improved glucose metabolism after Roux-en-Y gastric bypass; the…
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CLINICAL_TRIALS trial_result · 2013-12-04Clinical Trial Update: Effect of Glycemic Variability on Autonomic Tone in Hospitalized Patients With Type 2 Diabetes [Phase 4]
Phase 4 study evaluating whether glycemic variability influences autonomic tone in hospitalized patients with Type 2 diabetes mellitus. The …
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CLINICAL_TRIALS trial_result · 2013-12-03Clinical Trial Update: Efficacy and Safety of Alogliptin Plus Metformin Compared to Glipizide Plus Metformin in Patients With Type 2 Diabetes Mellitus [Phase 3]
Phase 3 trial comparing efficacy and safety of alogliptin plus metformin versus glipizide plus metformin in adults with type 2 diabetes; res…
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CLINICAL_TRIALS trial_result · 2013-12-03Clinical Trial Update: Evaluation of Continuous Glucose Monitoring in Participants With Type 2 Diabetes Mellitus (MK-0000-258 AM2) [Phase 1]
Merck conducted a Phase 1 clinical trial evaluating continuous glucose monitoring in participants with Type 2 diabetes mellitus. The study h…
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CLINICAL_TRIALS trial_result · 2013-12-02Clinical Trial Update: A Randomized Cross-over Trial of the Postprandial Effects of Three Different Diets in Patients With Type 2 Diabetes [NA]
Completed status for a randomized cross-over trial comparing the postprandial effects of three diets in patients with Type 2 Diabetes Mellit…
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: Trial Investigating the Safety of NNC 0113-0987 in Healthy Male Subjects [Phase 1]
A Phase 1 safety trial of the investigational diabetes drug NNC 0113-0987 in healthy male volunteers has been completed.
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: Saxagliptin Compared to Glimepiride in Elderly Type 2 Diabetes Patients, With Inadequate Glycemic Control on Metformin [Phase 4]
Phase 4 trial comparing saxagliptin to glimepiride in elderly patients with type 2 diabetes inadequately controlled on metformin; results ha…
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: GIP: Glucose-dependent Insulinotropic Peptide [Phase 1]
Phase 1 clinical trial update for GIP (glucose-dependent insulinotropic peptide) in Type 2 diabetes. The study status is completed.
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: GIP, GLP-1 and GLP-2 in Type 2 Diabetic Hyperglucagonemia
The trial evaluated incretin hormones GIP, GLP-1, and GLP-2 in individuals with Type 2 Diabetes Mellitus and is reported as completed.
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: A Trial Investigating the Effect of NN5401 in Subjects With Type 2 Diabetes [Phase 1]
A Phase 1 clinical trial evaluating NN5401 in subjects with Type 2 diabetes has been completed. The study was sponsored by Novo Nordisk A/S.
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of DA-1229 and Metformin After Oral Administration in Healthy Male Subjects [Phase 1]
A Phase 1 pharmacokinetic/pharmacodynamic study evaluating the drug-drug interaction between DA-1229 and metformin in healthy male subjects,…
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: A Trial Investigating the Effect of NN1250 in Japanese Subjects With Type 2 Diabetes [Phase 1]
A Phase 1 trial of NN1250 in Japanese subjects with Type 2 diabetes was terminated.
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: Effect of Arginine on Microcirculation in Patients With Diabetes [Phase 4]
A Phase 4 trial evaluating the effect of arginine on microcirculation in patients with type 2 diabetes has completed.
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: Self-Management Using Smartphone Application for Type2 DM in Real siTuation (SMART-DM) [NA]
A completed clinical trial evaluating a smartphone application for self-management in individuals with Type 2 Diabetes Mellitus.
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Targeting Inflammation Using Salsalate for Type 2 Diabetes-Stage II [Phase 2, Phase 3]
The update reports results from a Phase 2/Phase 3 study of salsalate for Type 2 Diabetes Mellitus. The trial is completed and results were p…
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CLINICAL_TRIALS research · 2013-11-25Clinical Trial Update: Changes in Glucose Metabolism After Roux-en-Y Gastric Bypass
Clinical trial update on how Roux-en-Y gastric bypass affects glucose metabolism in people with type 2 diabetes mellitus and obesity.
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Comparison of Two Biphasic Insulin Aspart 30 Treatment Regimens in Subjects With Type 2 Diabetes Not Achieving HbA1c Treatment Targets on OADs Alone [Phase 4]
Phase 4 trial comparing two regimens of biphasic insulin aspart 30 in adults with Type 2 diabetes not at HbA1c target on oral antidiabetic d…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Exercise and Type 2 Diabetes: Gender and Endothelial Function [NA]
This clinical trial update reports the completion of a study examining how exercise affects endothelial function in adults with Type 2 diabe…
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FDA approval · 2013-11-22FDA Approved: REPAGLINIDE — Original Application (Chartwell RX, LLC)
The FDA approved Chartwell RX, LLC's original Abbreviated New Drug Application for repaglinide, a meglitinide used to improve glycemic contr…
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CLINICAL_TRIALS trial_result · 2013-11-21Clinical Trial Update: Basal/Bolus Versus Sliding Scale Insulin In Hospitalized Patients With Type 2 Diabetes [Phase 4]
A Phase 4 trial comparing basal/bolus insulin with sliding-scale insulin in hospitalized patients with Type 2 diabetes has completed.
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CLINICAL_TRIALS trial_result · 2013-11-21Clinical Trial Update: Effects of Exercise Therapy on Ventricular and Endothelial Function in Patients After Coronary Artery Bypass Surgery
A completed clinical trial assessed how structured exercise therapy affects ventricular and endothelial function in patients after coronary …
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CLINICAL_TRIALS research · 2013-11-21Clinical Trial Update: DMBSS-A Randomized Trial of Different Laparoscopic Gastric Bypass Surgery in Patients With Obesity-related T2DM [NA]
This entry describes a randomized trial comparing different laparoscopic gastric bypass procedures in patients with obesity-related type 2 d…
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CLINICAL_TRIALS trial_result · 2013-11-19Clinical Trial Update: Efficacy and Safety Study of SHR117887 in Combination With Metformin in Patients With Type 2 Diabetes [Phase 2]
A Phase 2 study evaluating SHR117887 in combination with Metformin for Type 2 diabetes mellitus has completed.