Type 2 Diabetes Mellitus
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CLINICAL_TRIALS research · 2015-06-16Clinical Trial Update: ATP Release and Sympathetic Nerve Activity in Patients With Type II Diabetes [Phase 1, Phase 2]
An update on a Phase 1/2 clinical trial investigating ATP release and sympathetic nerve activity in patients with type 2 diabetes.
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CLINICAL_TRIALS trial_result · 2015-06-16Clinical Trial Update: Effectiveness of a Computerised Prompt for Primary and Secondary Care Physicians to Refer or Refer Back Type 2 Diabetes Patients [NA]
Completed clinical trial evaluating the effectiveness of a computerized prompt to influence referrals for Type 2 diabetes patients by primar…
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CLINICAL_TRIALS trial_result · 2015-06-16Clinical Trial Update: Metabolomic Analysis of Hepatic Insulin Resistance [NA]
This clinical trial update reports results from a metabolomic analysis of hepatic insulin resistance in participants with type 2 diabetes me…
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CLINICAL_TRIALS trial_result · 2015-06-16Clinical Trial Update: The Relation Between Plasma Irisin Level and Endothelial Dysfunction in Type 2 Diabetes
A completed clinical trial investigates the relationship between plasma irisin levels and endothelial dysfunction in people with Type 2 diab…
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Assessment of the Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Insufficiently Controlled With Basal Insulin +/- Metformin [Phase 3]
This update summarizes the completion of a Phase 3 trial evaluating the efficacy and safety of lixisenatide added to basal insulin (with or …
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: MK0767 in Type 2 Diabetes (0767-012) [Phase 2]
A Phase 2 trial of MK0767 for Type 2 Diabetes Mellitus was terminated.
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FDA approval · 2015-06-12FDA Approved: JANUMET — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approves a supplemental application for JANUMET (sitagliptin/metformin hydrochloride) from Merck Sharp & Dohme LLC, updating the labelin…
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FDA approval · 2015-06-12FDA Approved: INSULIN LISPRO — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for insulin lispro from Eli Lilly, resulting in an additional regulatory action for this product.
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: MK0767 and Sulfonylurea Combination Study (0767-027) [Phase 3]
A Phase 3 study (0767-027) evaluating MK-0767 in combination with a sulfonylurea for type 2 diabetes was terminated.
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: Study MK0767 and Metformin in Type 2 Diabetic Patients (0767-020) [Phase 3]
A Phase 3 study evaluating MK0767 in combination with Metformin for Type 2 diabetes has been terminated.
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: Evaluating Safety of NovoPen® 3 and/or FlexPen® Devices in Routine Clinical Practice
A completed clinical trial evaluated the safety of NovoPen 3 and FlexPen devices in routine clinical practice.
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: A Surgical Approach to the Management of Type II Diabetes Mellitus in Patients With a BMI Between 25-35 kg/m2 [NA]
The clinical trial evaluating a surgical approach to manage type 2 diabetes in overweight adults (BMI 25-35 kg/m2) has been terminated.
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: MK0767 Glipizide Comparator Cardiac Safety Study (0767-018) [Phase 3]
Phase 3 trial comparing MK0767 to glipizide for cardiac safety in type 2 diabetes was terminated.
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CLINICAL_TRIALS withdrawal · 2015-06-12Clinical Trial Update: Dyslipidemia in Type 2 Diabetes (0767-034) [Phase 3]
A Phase 3 clinical trial evaluating dyslipidemia in adults with type 2 diabetes (NCT00547274) was terminated.
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FDA approval · 2015-06-11FDA Approved: INSULIN LISPRO — Supplemental Application (Eli Lilly and Company)
The FDA approved a supplemental application for insulin lispro from Eli Lilly (Humalog). This action typically relates to labeling changes o…
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Safety and Tolerability Study of Oral LGD-6972 for Type 2 Diabetes Mellitus [Phase 1]
A Phase 1 safety and tolerability study of oral LGD-6972 in Type 2 Diabetes Mellitus has completed.
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CLINICAL_TRIALS trial_result · 2015-06-10Clinical Trial Update: Bioequivalence/Food Effect - Saxa/Dapa Dual Fixed Dose Combination (FDC) [Phase 1]
Phase 1 bioequivalence and food-effect evaluation of a Saxa/Dapa dual fixed-dose combination (saxagliptin + dapagliflozin) in type 2 diabete…
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CLINICAL_TRIALS trial_result · 2015-06-10Clinical Trial Update: Effect of Iron Reduction by Phlebotomy for Type 2 Diabetes [NA]
A completed clinical trial evaluating whether reducing body iron through phlebotomy impacts outcomes in people with Type 2 diabetes mellitus…
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CLINICAL_TRIALS trial_result · 2015-06-09Clinical Trial Update: A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Co-administration of Sitagliptin and Metformin as Individual Tablets (0431A-095) [Phase 1]
Phase 1 bioequivalence study comparing a sitagliptin/metformin combination tablet to co-administration of sitagliptin and metformin for Type…
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CLINICAL_TRIALS trial_result · 2015-06-09Clinical Trial Update: Therapeutic Efficacy of "Abroma Agusta" in HbA1c % in NIDDM
A clinical trial update evaluating the therapeutic efficacy of Abroma Agusta for reducing HbA1c levels in Type 2 diabetes mellitus.
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CLINICAL_TRIALS research · 2015-06-09Clinical Trial Update: Self-Management and Resourceful Transition of Type 2 Diabetes With Stage 3 Kidney Disease [NA]
This clinical trial update reports termination of a University of Colorado, Denver study focused on self-management and resourceful transiti…
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FDA approval · 2015-06-08FDA Approved: INVOKAMET — Supplemental Application (Janssen Pharmaceuticals, Inc.)
The FDA approved a supplemental application for INVOKAMET, the fixed-dose combination of canagliflozin and metformin hydrochloride, submitte…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: The Role of Vitamin D3 and Calcium Supplementation in Attenuating T2DM Severity [Phase 1]
This Phase 1 trial evaluated whether vitamin D3 with calcium supplementation could attenuate severity of Type 2 diabetes mellitus. The study…
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CLINICAL_TRIALS trial_result · 2015-06-04Clinical Trial Update: DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 Diabetes [Phase 4]
A Phase 4 trial reports that inhibition of DPP-4 enzymes may promote healing of chronic foot ulcers in people with type 2 diabetes.
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CLINICAL_TRIALS research · 2015-06-04Clinical Trial Update: Eating vs Skipping Breakfast on Postprandial Hyperglycemia After Lunch and Dinner in T2D [NA]
Tel Aviv University conducted a clinical trial comparing eating breakfast versus skipping breakfast and its effect on postprandial glucose a…